Gene: ENSMUSG00000024402 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000024402
Transcript Identifier
ENSMUST00000025266
Gene Type
Coding gene
Location
17 : 35203737-35204653 : negative

Family Information

Homologous gene family
HOM03P006776
(13 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
lymphotoxin A

Identifiers

Type Value
UniprotP09225
UniprotQ542S2
MGI104797

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001666
IEA
Genome Projectresponse to hypoxia
GO:0002876
IGI
Genome Projectpositive regulation of chronic inflammatory response to antigenic stimulus
GO:0002925
IGI
Genome Projectpositive regulation of humoral immune response mediated by circulating immunoglobulin
GO:0006927
TAS
Genome Projecttransformed cell apoptotic process
GO:0006954
TAS
Genome Projectinflammatory response
GO:0006955
IEA
Genome Projectimmune response
GO:0006959
IMP
Genome Projecthumoral immune response
GO:0007584
IEA
Genome Projectresponse to nutrient
GO:0008283
TAS
Genome Projectcell proliferation
GO:0008284
TAS
Genome Projectpositive regulation of cell proliferation
GO:0009987
TAS
Genome Projectcellular process
GO:0032496
IEA
Genome Projectresponse to lipopolysaccharide
GO:0032729
IGI
Genome Projectpositive regulation of interferon-gamma production
GO:0042493
IEA
Genome Projectresponse to drug
GO:0043065
IEA
Genome Projectpositive regulation of apoptotic process
GO:0044130
IGI
Genome Projectnegative regulation of growth of symbiont in host
GO:0048147
IEA
Genome Projectnegative regulation of fibroblast proliferation
GO:0048535
IMP
Genome Projectlymph node development
GO:0050830
IGI
Genome Projectdefense response to Gram-positive bacterium
GO:0060252
IEA
Genome Projectpositive regulation of glial cell proliferation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005125
IEA
Genome Projectcytokine activity
GO:0005164
TAS, IEA
Genome Projecttumor necrosis factor receptor binding
GO:0005515
IPI
Genome Projectprotein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005615
IEA
Genome Projectextracellular space
GO:0016020
IEA
Genome Projectmembrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR002960Lymphotoxin-alpha
IPR006052Tumour necrosis factor domain
IPR006053Tumour necrosis factor
IPR008983Tumour necrosis factor-like domain
IPR021184Tumour necrosis factor, conserved site

No MapMan annotations defined for this gene.