Gene: ENSMUSG00000024304 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000024304
Transcript Identifier
ENSMUST00000025166
Gene Type
Coding gene
Location
18 : 16590147-16808394 : negative

Family Information

Homologous gene family
HOM03P000124
(235 genes in 5 species)
specific family
Orthologous gene family
ORTHO03P009190
(9 genes in 2 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
cadherin 2

Identifiers

Type Value
UniprotP15116
MGI88355

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007155
IDA
IEA
Genome Projectcell adhesion
GO:0007156
IDA
IEA
Genome Projecthomophilic cell adhesion via plasma membrane adhesion molecules
GO:0007157
IDA
Genome Projectheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007416
IEA
Genome Projectsynapse assembly
GO:0009966
IEA
Genome Projectregulation of signal transduction
GO:0010001
IDA
Genome Projectglial cell differentiation
GO:0016337
IEA
Genome Projectsingle organismal cell-cell adhesion
GO:0016339
IDA
IEA
Genome Projectcalcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0016477
IDA
Genome Projectcell migration
GO:0021537
IGI
Genome Projecttelencephalon development
GO:0021987
IGI
Genome Projectcerebral cortex development
GO:0031641
IEA
Genome Projectregulation of myelination
GO:0032880
IEA
Genome Projectregulation of protein localization
GO:0035023
IEA
Genome Projectregulation of Rho protein signal transduction
GO:0043410
IGI
Genome Projectpositive regulation of MAPK cascade
GO:0044331
IDA
Genome Projectcell-cell adhesion mediated by cadherin
GO:0048514
IMP
Genome Projectblood vessel morphogenesis
GO:0048854
IGI
Genome Projectbrain morphogenesis
GO:0048872
IGI
Genome Projecthomeostasis of number of cells
GO:0050770
IEA
Genome Projectregulation of axonogenesis
GO:0051146
IGI
Genome Projectstriated muscle cell differentiation
GO:0051291
IEA
Genome Projectprotein heterooligomerization
GO:0060019
IGI
Genome Projectradial glial cell differentiation
GO:0060563
IGI
Genome Projectneuroepithelial cell differentiation
GO:0070445
IGI
Genome Projectregulation of oligodendrocyte progenitor proliferation
GO:0090002
IDA
Genome Projectestablishment of protein localization to plasma membrane
GO:0090090
IGI
Genome Projectnegative regulation of canonical Wnt signaling pathway
GO:0097118
IMP
Genome Projectneuroligin clustering involved in postsynaptic membrane assembly
GO:0097150
IDA
Genome Projectneuronal stem cell population maintenance
GO:1902897
IMP
Genome Projectregulation of postsynaptic density protein 95 clustering
GO:2000809
IMP
Genome Projectpositive regulation of synaptic vesicle clustering

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005509
IEA
Genome Projectcalcium ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008013
IEA
Genome Projectbeta-catenin binding
GO:0019899
IPI
Genome Projectenzyme binding
GO:0019901
IEA
Genome Projectprotein kinase binding
GO:0019903
IPI
Genome Projectprotein phosphatase binding
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0045294
ISO
IEA
Genome Projectalpha-catenin binding
GO:0045295
ISO
IEA
Genome Projectgamma-catenin binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0050998
IEA
Genome Projectnitric-oxide synthase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
IEA
Genome Projectplasma membrane
GO:0005911
IDA
ISO
IEA
Genome Projectcell-cell junction
GO:0005912
IDA
Genome Projectadherens junction
GO:0005913
ISO
IEA
Genome Projectcell-cell adherens junction
GO:0005916
IDA
IEA
Genome Projectfascia adherens
GO:0005925
ISO
IEA
Genome Projectfocal adhesion
GO:0014704
IDA
Genome Projectintercalated disc
GO:0016020
ISO
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0016323
IDA
Genome Projectbasolateral plasma membrane
GO:0016324
IDA
Genome Projectapical plasma membrane
GO:0016342
ISO
IEA
Genome Projectcatenin complex
GO:0030027
IDA
ISO
Genome Projectlamellipodium
GO:0043234
IEA
Genome Projectprotein complex
GO:0044853
IDA
Genome Projectplasma membrane raft
GO:0045202
IDA
IEA
Genome Projectsynapse
GO:0070062
ISO
IEA
Genome Projectextracellular exosome
GO:0030864
ISO
Genome Projectcortical actin cytoskeleton

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000233Cadherin, cytoplasmic domain
IPR002126Cadherin
IPR014868Cadherin prodomain
IPR015919Cadherin-like
IPR020894Cadherin conserved site
IPR027397Catenin binding domain
IPR030051N-cadherin

No MapMan annotations defined for this gene.