Gene: ENSMUSG00000024140 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000024140
Transcript Identifier
ENSMUST00000024954
Gene Type
Coding gene
Location
17 : 86754283-86831102 : positive

Family Information

Homologous gene family
HOM03P004831
(19 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P024249
(4 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
endothelial PAS domain protein 1

Identifiers

Type Value
UniprotP97481
MGI109169

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001525
IMP
IEA
Genome Projectangiogenesis
GO:0001666
IMP
ISO
IEA
Genome Projectresponse to hypoxia
GO:0001892
IGI
Genome Projectembryonic placenta development
GO:0001974
IMP
Genome Projectblood vessel remodeling
GO:0002027
IMP
Genome Projectregulation of heart rate
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006366
IDA
Genome Projecttranscription from RNA polymerase II promoter
GO:0006979
IMP, IGI
Genome Projectresponse to oxidative stress
GO:0007005
IMP
Genome Projectmitochondrion organization
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007601
IMP
Genome Projectvisual perception
GO:0030097
IMP
Genome Projecthemopoiesis
GO:0030154
IGI
IEA
Genome Projectcell differentiation
GO:0030218
IMP
Genome Projecterythrocyte differentiation
GO:0030324
IMP
Genome Projectlung development
GO:0042415
IMP
Genome Projectnorepinephrine metabolic process
GO:0043129
IMP
Genome Projectsurfactant homeostasis
GO:0043619
IDA, IMP
Genome Projectregulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0045944
IDA, IMP, IGI
ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048469
IMP
Genome Projectcell maturation
GO:0048625
IMP
Genome Projectmyoblast fate commitment
GO:0055072
IGI
Genome Projectiron ion homeostasis
GO:0071456
ISS, ISO
IEA
Genome Projectcellular response to hypoxia

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001077
IDA
Genome Projecttranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003677
IDA, IGI
ISO
IEA
Genome ProjectDNA binding
GO:0003700
IDA
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IPI
ISO
IEA
Genome Projecttranscription factor binding
GO:0035035
ISS, ISO
IEA
Genome Projecthistone acetyltransferase binding
GO:0043565
ISO
IEA
Genome Projectsequence-specific DNA binding
GO:0046982
IPI
ISO
IEA
Genome Projectprotein heterodimerization activity
GO:0046983
IEA
Genome Projectprotein dimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005667
IDA
ISO
IEA
Genome Projecttranscription factor complex
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0016607
IDA
IEA
Genome Projectnuclear speck

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000014PAS domain
IPR001067Nuclear translocator
IPR001610PAC motif
IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
IPR013655PAS fold-3
IPR013767PAS fold
IPR014887HIF-1 alpha, transactivation domain, C-terminal
IPR021537Hypoxia-inducible factor, alpha subunit

No MapMan annotations defined for this gene.