Gene: ENSMUSG00000022982 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000022982
Transcript Identifier
ENSMUST00000023707
Gene Type
Coding gene
Location
16 : 90220858-90226257 : positive

Family Information

Homologous gene family
HOM03P001059
(60 genes in 26 species)
specific family
Orthologous gene family
ORTHO03P004929
(17 genes in 14 species)
specific family

Descriptions

gene_descr
superoxide dismutase 1, soluble

Identifiers

Type Value
UniprotP08228
MGI98351

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000187
IDA
Genome Projectactivation of MAPK activity
GO:0000302
IMP
Genome Projectresponse to reactive oxygen species
GO:0000303
IMP
ISO
IEA
Genome Projectresponse to superoxide
GO:0001541
IMP
Genome Projectovarian follicle development
GO:0001819
ISS, ISO
IEA
Genome Projectpositive regulation of cytokine production
GO:0001895
IMP
Genome Projectretina homeostasis
GO:0001975
IEA
Genome Projectresponse to amphetamine
GO:0002262
IMP, IGI
Genome Projectmyeloid cell homeostasis
GO:0006749
IMP
Genome Projectglutathione metabolic process
GO:0006801
IMP
ISO
IEA
Genome Projectsuperoxide metabolic process
GO:0006879
IMP
Genome Projectcellular iron ion homeostasis
GO:0006979
IDA, IMP
IEA
Genome Projectresponse to oxidative stress
GO:0007283
IMP
Genome Projectspermatogenesis
GO:0007566
IMP
Genome Projectembryo implantation
GO:0007568
IMP
Genome Projectaging
GO:0007569
ISO
IEA
Genome Projectcell aging
GO:0007605
IMP
Genome Projectsensory perception of sound
GO:0007626
IMP
Genome Projectlocomotory behavior
GO:0008089
IMP
Genome Projectanterograde axon cargo transport
GO:0008090
IMP
Genome Projectretrograde axon cargo transport
GO:0008217
IMP
Genome Projectregulation of blood pressure
GO:0009408
IMP
Genome Projectresponse to heat
GO:0010033
ISS, ISO
IEA
Genome Projectresponse to organic substance
GO:0019226
IMP
Genome Projecttransmission of nerve impulse
GO:0019430
IMP, IGI
TAS
Genome Projectremoval of superoxide radicals
GO:0031667
IEA
Genome Projectresponse to nutrient levels
GO:0032287
IMP
Genome Projectperipheral nervous system myelin maintenance
GO:0032930
ISO
IEA
Genome Projectpositive regulation of superoxide anion generation
GO:0034465
IEA
Genome Projectresponse to carbon monoxide
GO:0034599
IEA
Genome Projectcellular response to oxidative stress
GO:0035865
IEA
Genome Projectcellular response to potassium ion
GO:0040014
IMP
Genome Projectregulation of multicellular organism growth
GO:0042493
IMP
Genome Projectresponse to drug
GO:0042542
IMP
Genome Projectresponse to hydrogen peroxide
GO:0042554
IDA
Genome Projectsuperoxide anion generation
GO:0043066
IDA, IMP
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043085
ISS, ISO
IEA
Genome Projectpositive regulation of catalytic activity
GO:0043087
ISO
IEA
Genome Projectregulation of GTPase activity
GO:0043524
IMP
Genome Projectnegative regulation of neuron apoptotic process
GO:0045471
IMP
Genome Projectresponse to ethanol
GO:0045541
ISS, ISO
IEA
Genome Projectnegative regulation of cholesterol biosynthetic process
GO:0045859
ISS, ISO
IEA
Genome Projectregulation of protein kinase activity
GO:0046677
IEA
Genome Projectresponse to antibiotic
GO:0046688
IEA
Genome Projectresponse to copper ion
GO:0046716
IMP
Genome Projectmuscle cell cellular homeostasis
GO:0048678
IMP
Genome Projectresponse to axon injury
GO:0050665
IMP
ISO
Genome Projecthydrogen peroxide biosynthetic process
GO:0051881
ISS, ISO
IEA
Genome Projectregulation of mitochondrial membrane potential
GO:0055114
IEA
Genome Projectoxidation-reduction process
GO:0060047
IMP
ISO
IEA
Genome Projectheart contraction
GO:0060052
IMP, IGI
Genome Projectneurofilament cytoskeleton organization
GO:0060087
IMP
Genome Projectrelaxation of vascular smooth muscle
GO:0060088
IMP
Genome Projectauditory receptor cell stereocilium organization
GO:0071276
IEA
Genome Projectcellular response to cadmium ion
GO:0071318
IEA
Genome Projectcellular response to ATP
GO:0072593
ISS, ISO
IEA
Genome Projectreactive oxygen species metabolic process
GO:0097332
IEA
Genome Projectresponse to antipsychotic drug
GO:1902177
ISO
IEA
Genome Projectpositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004784
IDA, IMP
ISO
TAS, IEA
Genome Projectsuperoxide dismutase activity
GO:0005507
ISS, ISO, IBA
IEA
Genome Projectcopper ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008270
ISS, ISO, IBA
IEA
Genome Projectzinc ion binding
GO:0016209
IEA
Genome Projectantioxidant activity
GO:0016491
IEA
Genome Projectoxidoreductase activity
GO:0019899
IEA
Genome Projectenzyme binding
GO:0030346
ISS, ISO
IEA
Genome Projectprotein phosphatase 2B binding
GO:0042802
ISO
IEA
Genome Projectidentical protein binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0048365
ISO
IEA
Genome ProjectRac GTPase binding
GO:0051087
ISS, ISO
IEA
Genome Projectchaperone binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005615
IDA
ISS, ISO
IEA
Genome Projectextracellular space
GO:0005634
ISS, ISO
IEA
Genome Projectnucleus
GO:0005654
ISO
IEA
Genome Projectnucleoplasm
GO:0005737
ISS, ISO
TAS, IEA
Genome Projectcytoplasm
GO:0005739
IDA
ISS, ISO
IEA
Genome Projectmitochondrion
GO:0005758
IEA
Genome Projectmitochondrial intermembrane space
GO:0005764
IEA
Genome Projectlysosome
GO:0005777
ISO
IEA
Genome Projectperoxisome
GO:0005829
ISS, ISO
IEA
Genome Projectcytosol
GO:0005886
ISS, ISO
IEA
Genome Projectplasma membrane
GO:0030141
IEA
Genome Projectsecretory granule
GO:0031012
ISS, ISO
IEA
Genome Projectextracellular matrix
GO:0031045
IEA
Genome Projectdense core granule
GO:0031410
ISS, ISO
IEA
Genome Projectcytoplasmic vesicle
GO:0032839
ISS, ISO
IEA
Genome Projectdendrite cytoplasm
GO:0043005
IEA
Genome Projectneuron projection
GO:0043025
ISS, ISO
IEA
Genome Projectneuronal cell body
GO:0043209
IDA
Genome Projectmyelin sheath
GO:0043234
ISS, ISO
IEA
Genome Projectprotein complex
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001424Superoxide dismutase, copper/zinc binding domain
IPR018152Superoxide dismutase, copper/zinc, binding site
IPR024134Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone

No MapMan annotations defined for this gene.