Gene: ENSMUSG00000022957 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000022957
Transcript Identifier
ENSMUST00000064797
Gene Type
Coding gene
Location
16 : 91782193-91912009 : positive

Family Information

Homologous gene family
HOM03P003304
(29 genes in 12 species)
specific family
Orthologous gene family
ORTHO03P017621
(5 genes in 4 species)
specific family

Descriptions

gene_descr
intersectin 1 (SH3 domain protein 1A)

Identifiers

Type Value
UniprotE9Q0N0
MGI1338069

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007264
IDA
Genome Projectsmall GTPase mediated signal transduction
GO:0035023
IEA
Genome Projectregulation of Rho protein signal transduction
GO:0035556
IEA
Genome Projectintracellular signal transduction
GO:0042327
IDA
Genome Projectpositive regulation of phosphorylation
GO:0043524
IMP
Genome Projectnegative regulation of neuron apoptotic process
GO:0043547
IEA
Genome Projectpositive regulation of GTPase activity
GO:0051897
IDA
Genome Projectpositive regulation of protein kinase B signaling

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005085
IEA
Genome Projectguanyl-nucleotide exchange factor activity
GO:0005089
IEA
Genome ProjectRho guanyl-nucleotide exchange factor activity
GO:0005509
IEA
Genome Projectcalcium ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0019209
IDA
Genome Projectkinase activator activity
GO:0032947
ISO
Genome Projectprotein complex scaffold
GO:0070064
ISO
Genome Projectproline-rich region binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
ISO
Genome Projectplasma membrane
GO:0005905
ISO
Genome Projectcoated pit
GO:0030027
IDA
Genome Projectlamellipodium
GO:0030139
IDA
Genome Projectendocytic vesicle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000008C2 domain
IPR000219Dbl homology (DH) domain
IPR000261EH domain
IPR001331Guanine-nucleotide dissociation stimulator, CDC24, conserved site
IPR001452SH3 domain
IPR001849Pleckstrin homology domain
IPR002048EF-hand domain
IPR011992EF-hand domain pair
IPR011993PH domain-like
IPR018247EF-Hand 1, calcium-binding site

No MapMan annotations defined for this gene.