Gene: ENSMUSG00000022952 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000022952
Transcript Identifier
ENSMUST00000023673
Gene Type
Coding gene
Location
16 : 92605655-92825646 : negative

Family Information

Homologous gene family
HOM03P008088
(10 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P073417
(2 genes in 2 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
runt related transcription factor 1

Identifiers

Type Value
UniprotQ3UM65
MGI99852

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001501
IMP
Genome Projectskeletal system development
GO:0001701
IMP
Genome Projectin utero embryonic development
GO:0001889
IMP
Genome Projectliver development
GO:0002318
IMP
Genome Projectmyeloid progenitor cell differentiation
GO:0006355
IDA
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006366
ISO
Genome Projecttranscription from RNA polymerase II promoter
GO:0007417
IMP
Genome Projectcentral nervous system development
GO:0008285
IMP
Genome Projectnegative regulation of cell proliferation
GO:0009966
IMP
Genome Projectregulation of signal transduction
GO:0030097
ISO
Genome Projecthemopoiesis
GO:0030099
ISO
IEA
Genome Projectmyeloid cell differentiation
GO:0030182
IMP
Genome Projectneuron differentiation
GO:0030853
ISO
IEA
Genome Projectnegative regulation of granulocyte differentiation
GO:0030854
ISO
IEA
Genome Projectpositive regulation of granulocyte differentiation
GO:0031069
IMP
Genome Projecthair follicle morphogenesis
GO:0032743
ISO
IEA
Genome Projectpositive regulation of interleukin-2 production
GO:0035162
IMP
Genome Projectembryonic hemopoiesis
GO:0045893
ISO
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA
ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048266
IMP
Genome Projectbehavioral response to pain
GO:0048666
IMP
Genome Projectneuron development
GO:0060216
IMP
Genome Projectdefinitive hemopoiesis
GO:0071336
IMP
Genome Projectregulation of hair follicle cell proliferation
GO:0071560
IDA
Genome Projectcellular response to transforming growth factor beta stimulus
GO:1903431
IMP
Genome Projectpositive regulation of cell maturation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000975
ISO
IEA
Genome Projectregulatory region DNA binding
GO:0000977
ISO
IEA
Genome ProjectRNA polymerase II regulatory region sequence-specific DNA binding
GO:0000981
IBA
Genome ProjectRNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0001047
ISO
IEA
Genome Projectcore promoter binding
GO:0001228
ISO
IEA
Genome Projecttranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0003677
IDA
ISO
IEA
Genome ProjectDNA binding
GO:0003700
IDA
ISO
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005509
ISO
IEA
Genome Projectcalcium ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0008134
ISO
IEA
Genome Projecttranscription factor binding
GO:0042803
ISO
IEA
Genome Projectprotein homodimerization activity
GO:0046982
ISO
IEA
Genome Projectprotein heterodimerization activity
GO:0070491
IPI
Genome Projectrepressing transcription factor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005604
IDA
Genome Projectbasement membrane
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005654
ISO
IEA
Genome Projectnucleoplasm
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0043231
ISO
IEA
Genome Projectintracellular membrane-bounded organelle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000040Acute myeloid leukemia 1 protein (AML1)/Runt
IPR008967p53-like transcription factor, DNA-binding
IPR012346p53/RUNT-type transcription factor, DNA-binding domain
IPR013524Runt domain
IPR013711Runx, C-terminal domain
IPR016554Runt-related transcription factor RUNX
IPR027384Runx, central domain

No MapMan annotations defined for this gene.