Gene: ENSMUSG00000022883 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000022883
Transcript Identifier
ENSMUST00000023600
Gene Type
Coding gene
Location
16 : 72664140-73044362 : positive

Family Information

Homologous gene family
HOM03P000274
(139 genes in 9 species)
specific family
Orthologous gene family
ORTHO03P011996
(7 genes in 4 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
roundabout homolog 1 (Drosophila)

Identifiers

Type Value
UniprotG5E843
MGI1274781

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002042
ISO
IEA
Genome Projectcell migration involved in sprouting angiogenesis
GO:0006919
ISO
IEA
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007156
ISO
IEA
Genome Projecthomophilic cell adhesion via plasma membrane adhesion molecules
GO:0007411
IMP, IGI
Genome Projectaxon guidance
GO:0008285
IMP
Genome Projectnegative regulation of cell proliferation
GO:0021836
ISO
IEA
Genome Projectchemorepulsion involved in postnatal olfactory bulb interneuron migration
GO:0033600
ISO
IEA
Genome Projectnegative regulation of mammary gland epithelial cell proliferation
GO:0035385
ISO
IEA
Genome ProjectRoundabout signaling pathway
GO:0050772
ISO
IEA
Genome Projectpositive regulation of axonogenesis
GO:0050925
ISO
IEA
Genome Projectnegative regulation of negative chemotaxis
GO:0060763
IMP
Genome Projectmammary duct terminal end bud growth
GO:0070100
ISO
IEA
Genome Projectnegative regulation of chemokine-mediated signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0030275
ISO
IEA
Genome ProjectLRR domain binding
GO:0042802
ISO
IEA
Genome Projectidentical protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0009986
ISO
IEA
Genome Projectcell surface
GO:0030673
IDA
Genome Projectaxolemma

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR003598Immunoglobulin subtype 2
IPR003961Fibronectin type III
IPR007110Immunoglobulin-like domain
IPR013098Immunoglobulin I-set
IPR013106Immunoglobulin V-set domain
IPR013783Immunoglobulin-like fold

No MapMan annotations defined for this gene.