Gene: ENSMUSG00000022812 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000022812
Transcript Identifier
ENSMUST00000114750
Gene Type
Coding gene
Location
16 : 38090526-38240569 : positive

Family Information

Homologous gene family
HOM03P000009
(1563 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000108
(79 genes in 38 species)
specific family

Descriptions

gene_descr
glycogen synthase kinase 3 beta

Identifiers

Type Value
UniprotE9QAQ5
MGI1861437

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000320
IDA
Genome Projectre-entry into mitotic cell cycle
GO:0001837
ISO
Genome Projectepithelial to mesenchymal transition
GO:0001954
ISO
Genome Projectpositive regulation of cell-matrix adhesion
GO:0005977
ISO
Genome Projectglycogen metabolic process
GO:0006468
IDA, IGI
ISO
IEA
Genome Projectprotein phosphorylation
GO:0006611
IDA
Genome Projectprotein export from nucleus
GO:0006983
IDA
ISO
Genome ProjectER overload response
GO:0007409
IGI
Genome Projectaxonogenesis
GO:0007520
IDA, IGI
Genome Projectmyoblast fusion
GO:0008283
TAS
Genome Projectcell proliferation
GO:0009887
IMP
Genome Projectorgan morphogenesis
GO:0010614
IDA
Genome Projectnegative regulation of cardiac muscle hypertrophy
GO:0010800
IDA
Genome Projectpositive regulation of peptidyl-threonine phosphorylation
GO:0010975
IGI
Genome Projectregulation of neuron projection development
GO:0010977
IMP, IGI
Genome Projectnegative regulation of neuron projection development
GO:0014043
IGI
Genome Projectnegative regulation of neuron maturation
GO:0014902
IGI
Genome Projectmyotube differentiation
GO:0016055
IGI
Genome ProjectWnt signaling pathway
GO:0016477
IGI
Genome Projectcell migration
GO:0018105
IDA
ISO
Genome Projectpeptidyl-serine phosphorylation
GO:0021766
ISO
Genome Projecthippocampus development
GO:0031333
ISO
Genome Projectnegative regulation of protein complex assembly
GO:0031334
ISO
Genome Projectpositive regulation of protein complex assembly
GO:0032091
ISO
Genome Projectnegative regulation of protein binding
GO:0032092
IDA
Genome Projectpositive regulation of protein binding
GO:0032436
IGI
Genome Projectpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032886
ISO
Genome Projectregulation of microtubule-based process
GO:0033138
IDA
Genome Projectpositive regulation of peptidyl-serine phosphorylation
GO:0035372
IGI
Genome Projectprotein localization to microtubule
GO:0035556
ISO
Genome Projectintracellular signal transduction
GO:0043066
IMP
ISO
Genome Projectnegative regulation of apoptotic process
GO:0043547
ISO
Genome Projectpositive regulation of GTPase activity
GO:0045444
IDA
Genome Projectfat cell differentiation
GO:0045773
IGI
Genome Projectpositive regulation of axon extension
GO:0045944
IMP
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046777
ISO
Genome Projectprotein autophosphorylation
GO:0046827
ISO
Genome Projectpositive regulation of protein export from nucleus
GO:0051534
ISO
Genome Projectnegative regulation of NFAT protein import into nucleus
GO:0060070
IDA
ISO
Genome Projectcanonical Wnt signaling pathway
GO:0071109
ISO
Genome Projectsuperior temporal gyrus development
GO:2000738
IMP
Genome Projectpositive regulation of stem cell differentiation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0001085
ISO
Genome ProjectRNA polymerase II transcription factor binding
GO:0002039
ISO
Genome Projectp53 binding
GO:0004672
IDA
IEA
Genome Projectprotein kinase activity
GO:0004674
IDA, IMP
ISS, ISO
Genome Projectprotein serine/threonine kinase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0008013
IPI
ISO
Genome Projectbeta-catenin binding
GO:0016301
ISO
Genome Projectkinase activity
GO:0019901
ISO
Genome Projectprotein kinase binding
GO:0031625
ISO
Genome Projectubiquitin protein ligase binding
GO:0034236
ISO
Genome Projectprotein kinase A catalytic subunit binding
GO:0050321
IDA
ISO
Genome Projecttau-protein kinase activity
GO:0051059
ISO
Genome ProjectNF-kappaB binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
Genome Projectnucleus
GO:0005654
ISO
Genome Projectnucleoplasm
GO:0005737
ISO
Genome Projectcytoplasm
GO:0005813
ISO
Genome Projectcentrosome
GO:0005829
IDA
Genome Projectcytosol
GO:0005886
ISO
Genome Projectplasma membrane
GO:0030426
IDA
Genome Projectgrowth cone
GO:0030529
IDA
Genome Projectintracellular ribonucleoprotein complex
GO:0030877
IDA
ISO
Genome Projectbeta-catenin destruction complex
GO:0043025
IDA
Genome Projectneuronal cell body
GO:0043198
IDA
Genome Projectdendritic shaft
GO:0043227
IDA
Genome Projectmembrane-bounded organelle
GO:0044297
IDA
Genome Projectcell body
GO:0097481
IDA
Genome Projectneuronal postsynaptic density

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000719Protein kinase domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR017441Protein kinase, ATP binding site

No MapMan annotations defined for this gene.