Gene: ENSMUSG00000022676 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000022676
Transcript Identifier
ENSMUST00000023356
Gene Type
Coding gene
Location
16 : 14705974-14708296 : positive

Family Information

Homologous gene family
HOM03P000007
(1601 genes in 28 species)
specific family
Orthologous gene family
ORTHO03P021460
(5 genes in 4 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
snail family zinc finger 2

Identifiers

Type Value
UniprotP97469
UniprotQ3UZ96
MGI1096393

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA
ISO
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001649
IEA
Genome Projectosteoblast differentiation
GO:0001837
IMP
ISO
IEA
Genome Projectepithelial to mesenchymal transition
GO:0003198
IMP
Genome Projectepithelial to mesenchymal transition involved in endocardial cushion formation
GO:0003273
IMP
Genome Projectcell migration involved in endocardial cushion formation
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IEA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0006933
IMP
Genome Projectnegative regulation of cell adhesion involved in substrate-bound cell migration
GO:0007219
ISS, ISO
IEA
Genome ProjectNotch signaling pathway
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007605
IMP
ISO
IEA
Genome Projectsensory perception of sound
GO:0009314
IDA, IMP
Genome Projectresponse to radiation
GO:0010839
ISO
IEA
Genome Projectnegative regulation of keratinocyte proliferation
GO:0010957
ISO
IEA
Genome Projectnegative regulation of vitamin D biosynthetic process
GO:0014032
ISO
IEA
Genome Projectneural crest cell development
GO:0016477
IGI
Genome Projectcell migration
GO:0030335
ISO
IEA
Genome Projectpositive regulation of cell migration
GO:0032331
ISO
IEA
Genome Projectnegative regulation of chondrocyte differentiation
GO:0032642
ISO
IEA
Genome Projectregulation of chemokine production
GO:0035066
IMP
Genome Projectpositive regulation of histone acetylation
GO:0035414
ISO
IEA
Genome Projectnegative regulation of catenin import into nucleus
GO:0035921
IMP
ISO
IEA
Genome Projectdesmosome disassembly
GO:0036120
TAS
Genome Projectcellular response to platelet-derived growth factor stimulus
GO:0042981
IC
Genome Projectregulation of apoptotic process
GO:0043066
IGI
Genome Projectnegative regulation of apoptotic process
GO:0043473
IMP
ISO
IEA
Genome Projectpigmentation
GO:0043518
ISO
IEA
Genome Projectnegative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0044319
TAS
Genome Projectwound healing, spreading of cells
GO:0044344
IEA
Genome Projectcellular response to fibroblast growth factor stimulus
GO:0045600
IMP, IGI
Genome Projectpositive regulation of fat cell differentiation
GO:0045667
ISO
IEA
Genome Projectregulation of osteoblast differentiation
GO:0050872
IMP
Genome Projectwhite fat cell differentiation
GO:0060021
IMP, IGI
Genome Projectpalate development
GO:0060070
ISO
IEA
Genome Projectcanonical Wnt signaling pathway
GO:0060429
IMP
Genome Projectepithelium development
GO:0060536
IGI
Genome Projectcartilage morphogenesis
GO:0060693
IMP
Genome Projectregulation of branching involved in salivary gland morphogenesis
GO:0070563
ISO
IEA
Genome Projectnegative regulation of vitamin D receptor signaling pathway
GO:0071364
ISO
IEA
Genome Projectcellular response to epidermal growth factor stimulus
GO:0071479
IGI
Genome Projectcellular response to ionizing radiation
GO:0090090
ISO
IEA
Genome Projectnegative regulation of canonical Wnt signaling pathway
GO:1900387
ISO
IEA
Genome Projectnegative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter
GO:1902230
ISO
IEA
Genome Projectnegative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:2000647
IMP
Genome Projectnegative regulation of stem cell proliferation
GO:2000810
ISO
IEA
Genome Projectregulation of bicellular tight junction assembly
GO:2000811
ISO
IEA
Genome Projectnegative regulation of anoikis
GO:2001028
IC
Genome Projectpositive regulation of endothelial cell chemotaxis
GO:2001240
IDA
Genome Projectnegative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001078
IDA, IGI
ISO
IEA
Genome Projecttranscriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003676
IEA
Genome Projectnucleic acid binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003682
IDA
Genome Projectchromatin binding
GO:0003700
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003705
IDA
Genome Projecttranscription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0043565
ISO
IEA
Genome Projectsequence-specific DNA binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000790
ISO
IEA
Genome Projectnuclear chromatin
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005737
IDA
IEA
Genome Projectcytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR007087Zinc finger, C2H2
IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
IPR015880Zinc finger, C2H2-like

No MapMan annotations defined for this gene.