Gene: ENSMUSG00000022637 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000022637
Transcript Identifier
ENSMUST00000114471
Gene Type
Coding gene
Location
16 : 52033023-52204692 : positive

Family Information

Homologous gene family
HOM03P011706
(7 genes in 4 species)
specific family

Descriptions

gene_descr
Casitas B-lineage lymphoma b

Identifiers

Type Value
UniprotB9EKI5
MGI2146430

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002669
IMP
Genome Projectpositive regulation of T cell anergy
GO:0006955
IMP
Genome Projectimmune response
GO:0007166
IEA
Genome Projectcell surface receptor signaling pathway
GO:0016567
IEA
Genome Projectprotein ubiquitination
GO:0023051
IEA
Genome Projectregulation of signaling
GO:0035556
IMP
Genome Projectintracellular signal transduction
GO:0042110
IMP
Genome ProjectT cell activation
GO:0045732
IMP
Genome Projectpositive regulation of protein catabolic process
GO:0046642
IMP
Genome Projectnegative regulation of alpha-beta T cell proliferation
GO:0050860
IMP
Genome Projectnegative regulation of T cell receptor signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001784
IEA
Genome Projectphosphotyrosine binding
GO:0004842
IEA
Genome Projectubiquitin-protein transferase activity
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0005509
IEA
Genome Projectcalcium ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
Genome Projectnucleus
GO:0005654
ISO
IEA
Genome Projectnucleoplasm
GO:0005737
ISO
IEA
Genome Projectcytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000980SH2 domain
IPR001841Zinc finger, RING-type
IPR003153Adaptor protein Cbl, N-terminal helical
IPR011992EF-hand domain pair
IPR013083Zinc finger, RING/FYVE/PHD-type
IPR014741Adaptor protein Cbl, EF hand-like
IPR014742Adaptor protein Cbl, SH2-like
IPR015940Ubiquitin-associated domain
IPR017907Zinc finger, RING-type, conserved site
IPR024159Adaptor protein Cbl, PTB domain
IPR024162Adaptor protein Cbl

No MapMan annotations defined for this gene.