Gene: ENSMUSG00000022521 (Mus musculus)

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Gene Identifier
ENSMUSG00000022521
Transcript Identifier
ENSMUST00000023165
Gene Type
Coding gene
Location
16 : 4084048-4213223 : negative

Family Information

Homologous gene family
HOM03P000396
(112 genes in 32 species)
specific family
Orthologous gene family
ORTHO03P000514
(48 genes in 30 species)
specific family

Descriptions

gene_descr
CREB binding protein

Identifiers

Type Value
UniprotF8VPR5
MGI1098280

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
ISO
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0006355
IDA
ISO
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006366
IDA
Genome Projecttranscription from RNA polymerase II promoter
GO:0006473
ISO
Genome Projectprotein acetylation
GO:0008283
IEA
Genome Projectcell proliferation
GO:0016573
ISO
IEA
Genome Projecthistone acetylation
GO:0018076
ISO
IEA
Genome ProjectN-terminal peptidyl-lysine acetylation
GO:0030718
IMP
Genome Projectgerm-line stem cell population maintenance
GO:0034644
ISO
Genome Projectcellular response to UV
GO:0045893
IDA
ISO
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IGI
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0070555
IEA
Genome Projectresponse to interleukin-1
GO:1900087
IEA
Genome Projectpositive regulation of G1/S transition of mitotic cell cycle

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000977
IDA
Genome ProjectRNA polymerase II regulatory region sequence-specific DNA binding
GO:0000987
ISO
IEA
Genome Projectcore promoter proximal region sequence-specific DNA binding
GO:0001078
ISO
IEA
Genome Projecttranscriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001085
ISO
IEA
Genome ProjectRNA polymerase II transcription factor binding
GO:0001191
ISO
IEA
Genome Projecttranscriptional repressor activity, RNA polymerase II transcription factor binding
GO:0001228
IDA
Genome Projecttranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0002039
ISO
IEA
Genome Projectp53 binding
GO:0003677
IDA
Genome ProjectDNA binding
GO:0003682
IDA
ISO
Genome Projectchromatin binding
GO:0003684
ISO
Genome Projectdamaged DNA binding
GO:0003700
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003712
IEA
Genome Projecttranscription cofactor activity
GO:0003713
ISO
IEA
Genome Projecttranscription coactivator activity
GO:0004402
IDA
ISO
IEA
Genome Projecthistone acetyltransferase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
ISO
IEA
Genome Projecttranscription factor binding
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0016407
IDA
ISO
IEA
Genome Projectacetyltransferase activity
GO:0033613
IEA
Genome Projectactivating transcription factor binding
GO:0042975
IEA
Genome Projectperoxisome proliferator activated receptor binding
GO:0043426
ISO
IEA
Genome ProjectMRF binding
GO:0046332
IEA
Genome ProjectSMAD binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000123
IDA
IEA
Genome Projecthistone acetyltransferase complex
GO:0000790
ISO
IEA
Genome Projectnuclear chromatin
GO:0000940
IDA
Genome Projectcondensed chromosome outer kinetochore
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005654
ISO
IEA
Genome Projectnucleoplasm
GO:0005667
IDA
Genome Projecttranscription factor complex
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0016604
ISO
IEA
Genome Projectnuclear body
GO:0016605
ISO
Genome ProjectPML body
GO:0043234
IEA
Genome Projectprotein complex
GO:0090575
IDA
Genome ProjectRNA polymerase II transcription factor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000197Zinc finger, TAZ-type
IPR000433Zinc finger, ZZ-type
IPR001487Bromodomain
IPR003101Coactivator CBP, KIX domain
IPR009110Nuclear receptor coactivator, interlocking
IPR010303Domain of unknown function DUF902, CREBbp
IPR013178Histone acetyltransferase Rtt109/CBP
IPR014744Nuclear receptor coactivator, CREB-bp-like, interlocking
IPR018359Bromodomain, conserved site
IPR031162CBP/p300-type histone acetyltransferase domain

No MapMan annotations defined for this gene.