Gene: ENSMUSG00000022346 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000022346
Transcript Identifier
ENSMUST00000022971
Gene Type
Coding gene
Location
15 : 61985922-61989908 : positive

Family Information

Homologous gene family
HOM03P125868
(orphan gene)
specific family

Descriptions

gene_descr
myelocytomatosis oncogene

Identifiers

Type Value
UniprotF8WID3
MGI97250

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA
ISO
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0000165
ISO
Genome ProjectMAPK cascade
GO:0001783
IMP
Genome ProjectB cell apoptotic process
GO:0002904
IGI
Genome Projectpositive regulation of B cell apoptotic process
GO:0006338
ISO
Genome Projectchromatin remodeling
GO:0006355
IGI
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006366
ISO
Genome Projecttranscription from RNA polymerase II promoter
GO:0006879
ISO
Genome Projectcellular iron ion homeostasis
GO:0006919
IDA
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006974
IDA
ISO
Genome Projectcellular response to DNA damage stimulus
GO:0007050
ISO
Genome Projectcell cycle arrest
GO:0008284
IDA, IGI
ISO
Genome Projectpositive regulation of cell proliferation
GO:0008630
IDA, IMP
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage
GO:0009314
IDA, IMP
Genome Projectresponse to radiation
GO:0010332
ISO
Genome Projectresponse to gamma radiation
GO:0010468
IDA
ISO
Genome Projectregulation of gene expression
GO:0016055
IDA
Genome ProjectWnt signaling pathway
GO:0016485
IMP
Genome Projectprotein processing
GO:0032091
IDA
Genome Projectnegative regulation of protein binding
GO:0032204
ISO
Genome Projectregulation of telomere maintenance
GO:0035457
IDA
Genome Projectcellular response to interferon-alpha
GO:0035690
ISO
Genome Projectcellular response to drug
GO:0035914
IMP
Genome Projectskeletal muscle cell differentiation
GO:0042474
IMP
Genome Projectmiddle ear morphogenesis
GO:0042981
IDA, IMP
Genome Projectregulation of apoptotic process
GO:0043085
IMP
Genome Projectpositive regulation of catalytic activity
GO:0043279
IMP
Genome Projectresponse to alkaloid
GO:0043280
ISO
Genome Projectpositive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043473
IMP
Genome Projectpigmentation
GO:0044336
IGI
Genome Projectcanonical Wnt signaling pathway involved in negative regulation of apoptotic process
GO:0044337
IGI
Genome Projectcanonical Wnt signaling pathway involved in positive regulation of apoptotic process
GO:0045656
ISO
Genome Projectnegative regulation of monocyte differentiation
GO:0045893
ISO
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA, IMP
ISO
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048146
ISO
Genome Projectpositive regulation of fibroblast proliferation
GO:0048147
ISO
Genome Projectnegative regulation of fibroblast proliferation
GO:0048705
IMP
Genome Projectskeletal system morphogenesis
GO:0050679
ISO
Genome Projectpositive regulation of epithelial cell proliferation
GO:0050910
IMP
Genome Projectdetection of mechanical stimulus involved in sensory perception of sound
GO:0051276
ISO
Genome Projectchromosome organization
GO:0051782
ISO
Genome Projectnegative regulation of cell division
GO:0060070
ISO
Genome Projectcanonical Wnt signaling pathway
GO:2000573
ISO
Genome Projectpositive regulation of DNA biosynthetic process
GO:2001022
ISO
Genome Projectpositive regulation of response to DNA damage stimulus
GO:2001235
IDA, IMP
Genome Projectpositive regulation of apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000978
ISO
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000987
IDA
Genome Projectcore promoter proximal region sequence-specific DNA binding
GO:0001077
ISO
Genome Projecttranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003677
IDA
Genome ProjectDNA binding
GO:0003700
ISO
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
ISO
Genome Projecttranscription factor binding
GO:0032403
ISO
Genome Projectprotein complex binding
GO:0046983
IEA
Genome Projectprotein dimerization activity
GO:0070491
ISO
Genome Projectrepressing transcription factor binding
GO:0070888
ISO
Genome ProjectE-box binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005654
ISO
Genome Projectnucleoplasm
GO:0005730
ISO
Genome Projectnucleolus
GO:0005819
IDA
Genome Projectspindle
GO:0016604
IDA
Genome Projectnuclear body
GO:0030424
IDA
Genome Projectaxon
GO:0043234
ISO
Genome Projectprotein complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR002418Transcription regulator Myc
IPR003327Leucine zipper, Myc
IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
IPR012682Transcription regulator Myc, N-terminal

No MapMan annotations defined for this gene.