Gene: ENSMUSG00000022191 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000022191
Transcript Identifier
ENSMUST00000090292
Gene Type
Coding gene
Location
15 : 12827276-12935122 : positive

Family Information

Homologous gene family
HOM03P007631
(11 genes in 10 species)
specific family

Descriptions

gene_descr
drosha, ribonuclease type III

Identifiers

Type Value
UniprotQ5HZJ0
MGI1261425

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006396
IEA
Genome ProjectRNA processing
GO:0010468
IMP
Genome Projectregulation of gene expression
GO:0010586
IMP
Genome ProjectmiRNA metabolic process
GO:0010628
IMP
Genome Projectpositive regulation of gene expression
GO:0016075
IEA
Genome ProjectrRNA catabolic process
GO:0030422
IBA
Genome Projectproduction of siRNA involved in RNA interference
GO:0031053
ISO, IBA
IEA
Genome Projectprimary miRNA processing
GO:0031054
IDA
Genome Projectpre-miRNA processing
GO:0042254
IEA
Genome Projectribosome biogenesis
GO:0050829
ISO
IEA
Genome Projectdefense response to Gram-negative bacterium
GO:0050830
ISO
IEA
Genome Projectdefense response to Gram-positive bacterium
GO:0090501
ISO
IEA
Genome ProjectRNA phosphodiester bond hydrolysis
GO:0090502
ISO, IBA
Genome ProjectRNA phosphodiester bond hydrolysis, endonucleolytic
GO:2000628
IMP
Genome Projectregulation of miRNA metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001530
ISO
IEA
Genome Projectlipopolysaccharide binding
GO:0003723
IEA
Genome ProjectRNA binding
GO:0003725
IBA
Genome Projectdouble-stranded RNA binding
GO:0004518
IEA
Genome Projectnuclease activity
GO:0004519
IEA
Genome Projectendonuclease activity
GO:0004521
IDA
Genome Projectendoribonuclease activity
GO:0004525
ISO, IBA
IEA
Genome Projectribonuclease III activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0042803
ISO
IEA
Genome Projectprotein homodimerization activity
GO:0044822
ISO
IEA
Genome Projectpoly(A) RNA binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IBA
IEA
Genome Projectnucleus
GO:0005730
IEA
Genome Projectnucleolus
GO:0070877
ISO
IEA
Genome Projectmicroprocessor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000999Ribonuclease III domain
IPR011907Ribonuclease III
IPR014720Double-stranded RNA-binding domain

No MapMan annotations defined for this gene.