Gene: ENSMUSG00000022061 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000022061
Transcript Identifier
ENSMUST00000022646
Gene Type
Coding gene
Location
14 : 69190705-69192248 : positive

Family Information

Homologous gene family
HOM03P000104
(258 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P067388
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate   and   Block duplicate

Descriptions

gene_descr
NK-3 transcription factor, locus 1 (Drosophila)

Identifiers

Type Value
UniprotP97436
UniprotQ3UVH8
MGI97352

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001655
IEP
TAS
Genome Projecturogenital system development
GO:0001656
IEP
Genome Projectmetanephros development
GO:0001756
IEP
Genome Projectsomitogenesis
GO:0001934
ISS, ISO
IEA
Genome Projectpositive regulation of protein phosphorylation
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006919
ISS, ISO
IEA
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007431
IMP
Genome Projectsalivary gland development
GO:0007507
IEP
Genome Projectheart development
GO:0008284
ISS, ISO
IEA
Genome Projectpositive regulation of cell proliferation
GO:0008285
IGI
ISO
IEA
Genome Projectnegative regulation of cell proliferation
GO:0008584
IEP
Genome Projectmale gonad development
GO:0010628
ISS, ISO
IEA
Genome Projectpositive regulation of gene expression
GO:0010629
ISO
IEA
Genome Projectnegative regulation of gene expression
GO:0010942
ISS, ISO
IEA
Genome Projectpositive regulation of cell death
GO:0014068
ISS, ISO
IEA
Genome Projectpositive regulation of phosphatidylinositol 3-kinase signaling
GO:0030521
ISS, ISO
IEA
Genome Projectandrogen receptor signaling pathway
GO:0030850
IEP
TAS
Genome Projectprostate gland development
GO:0032147
ISO
Genome Projectactivation of protein kinase activity
GO:0033574
IMP
Genome Projectresponse to testosterone
GO:0035260
TAS
Genome Projectinternal genitalia morphogenesis
GO:0035690
IEA
Genome Projectcellular response to drug
GO:0035907
IEP
Genome Projectdorsal aorta development
GO:0043280
ISS, ISO
IEA
Genome Projectpositive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043401
ISO
IEA
Genome Projectsteroid hormone mediated signaling pathway
GO:0043491
IMP
ISO
IEA
Genome Projectprotein kinase B signaling
GO:0043569
IDA
Genome Projectnegative regulation of insulin-like growth factor receptor signaling pathway
GO:0045860
IEA
Genome Projectpositive regulation of protein kinase activity
GO:0045892
IMP
ISS, ISO
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
IDA
ISO
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045930
ISO
IEA
Genome Projectnegative regulation of mitotic cell cycle
GO:0045931
ISS, ISO
IEA
Genome Projectpositive regulation of mitotic cell cycle
GO:0045944
ISS, ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048754
IMP
Genome Projectbranching morphogenesis of an epithelial tube
GO:0050680
IMP
Genome Projectnegative regulation of epithelial cell proliferation
GO:0051781
ISS, ISO
IEA
Genome Projectpositive regulation of cell division
GO:0060037
IEP
Genome Projectpharyngeal system development
GO:0060442
IMP
Genome Projectbranching involved in prostate gland morphogenesis
GO:0060664
IMP
Genome Projectepithelial cell proliferation involved in salivary gland morphogenesis
GO:0060770
IMP
Genome Projectnegative regulation of epithelial cell proliferation involved in prostate gland development
GO:0071347
IEA
Genome Projectcellular response to interleukin-1
GO:0071356
IEA
Genome Projectcellular response to tumor necrosis factor
GO:0071383
ISS, ISO
IEA
Genome Projectcellular response to steroid hormone stimulus
GO:0071456
ISO
IEA
Genome Projectcellular response to hypoxia
GO:0071850
ISO
IEA
Genome Projectmitotic cell cycle arrest
GO:0071899
ISS, ISO
IEA
Genome Projectnegative regulation of estrogen receptor binding
GO:2000836
ISS, ISO
IEA
Genome Projectpositive regulation of androgen secretion
GO:2001022
ISS, ISO
IEA
Genome Projectpositive regulation of response to DNA damage stimulus
GO:2001235
ISO
IEA
Genome Projectpositive regulation of apoptotic signaling pathway
GO:2001244
ISS, ISO
IEA
Genome Projectpositive regulation of intrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000976
ISS, ISO
IEA
Genome Projecttranscription regulatory region sequence-specific DNA binding
GO:0001047
ISS, ISO
IEA
Genome Projectcore promoter binding
GO:0003677
IDA
IEA
Genome ProjectDNA binding
GO:0003700
IDA
ISO
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0004882
ISS, ISO
IEA
Genome Projectandrogen receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IDA, IPI
ISO
IEA
Genome Projecttranscription factor binding
GO:0008656
ISO
IEA
Genome Projectcysteine-type endopeptidase activator activity involved in apoptotic process
GO:0030284
ISS, ISO
IEA
Genome Projectestrogen receptor activity
GO:0030295
ISS, ISO
IEA
Genome Projectprotein kinase activator activity
GO:0030331
ISS, ISO
IEA
Genome Projectestrogen receptor binding
GO:0042826
ISO
IEA
Genome Projecthistone deacetylase binding
GO:0043565
IDA
ISO
IEA
Genome Projectsequence-specific DNA binding
GO:0043621
ISS, ISO
IEA
Genome Projectprotein self-association
GO:0044212
ISO
IEA
Genome Projecttranscription regulatory region DNA binding
GO:0097162
IDA
Genome ProjectMADS box domain binding
GO:0000983
IMP
Genome Projecttranscription factor activity, RNA polymerase II core promoter sequence-specific

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
IDA
ISO
IEA
Genome Projectintracellular
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001356Homeobox domain
IPR009057Homeodomain-like
IPR017970Homeobox, conserved site
IPR020479Homeodomain, metazoa

No MapMan annotations defined for this gene.