Gene: ENSMUSG00000022015 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000022015
Transcript Identifier
ENSMUST00000022592
Gene Type
Coding gene
Location
14 : 78278576-78307889 : negative

Family Information

Homologous gene family
HOM03P034779
(2 genes in 2 species)
specific family

Descriptions

gene_descr
tumor necrosis factor (ligand) superfamily, member 11

Identifiers

Type Value
UniprotO35235
MGI1100089

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001503
IMP
Genome Projectossification
GO:0002158
IDA
Genome Projectosteoclast proliferation
GO:0002548
ISO
IEA
Genome Projectmonocyte chemotaxis
GO:0006955
IEA
Genome Projectimmune response
GO:0007257
IDA
Genome Projectactivation of JUN kinase activity
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0009887
IMP
Genome Projectorgan morphogenesis
GO:0019221
ISO
IEA
Genome Projectcytokine-mediated signaling pathway
GO:0030154
IEA
Genome Projectcell differentiation
GO:0030316
IDA, IMP, IGI
ISO
Genome Projectosteoclast differentiation
GO:0033209
IGI
Genome Projecttumor necrosis factor-mediated signaling pathway
GO:0033598
IMP
Genome Projectmammary gland epithelial cell proliferation
GO:0034112
ISO
IEA
Genome Projectpositive regulation of homotypic cell-cell adhesion
GO:0038001
IDA
Genome Projectparacrine signaling
GO:0042327
IDA
Genome Projectpositive regulation of phosphorylation
GO:0043123
IDA
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043406
ISO
IEA
Genome Projectpositive regulation of MAP kinase activity
GO:0045453
IDA
Genome Projectbone resorption
GO:0045670
IDA
Genome Projectregulation of osteoclast differentiation
GO:0045672
IDA, IGI
ISO
IEA
Genome Projectpositive regulation of osteoclast differentiation
GO:0045780
ISO
IEA
Genome Projectpositive regulation of bone resorption
GO:0045944
ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046330
IGI
Genome Projectpositive regulation of JNK cascade
GO:0048535
TAS
Genome Projectlymph node development
GO:0050870
ISO
IEA
Genome Projectpositive regulation of T cell activation
GO:0051091
IDA
Genome Projectpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0051092
ISO
IEA
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0051260
IDA
Genome Projectprotein homooligomerization
GO:0051466
IDA
Genome Projectpositive regulation of corticotropin-releasing hormone secretion
GO:0051897
IMP
Genome Projectpositive regulation of protein kinase B signaling
GO:0055074
IGI
Genome Projectcalcium ion homeostasis
GO:0060749
IMP
Genome Projectmammary gland alveolus development
GO:0070371
IDA
Genome ProjectERK1 and ERK2 cascade
GO:0071812
IDA
Genome Projectpositive regulation of fever generation by positive regulation of prostaglandin secretion
GO:0071847
ISO
IEA
Genome ProjectTNFSF11-mediated signaling pathway
GO:0071848
ISO
IEA
Genome Projectpositive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling
GO:1902533
ISO
IEA
Genome Projectpositive regulation of intracellular signal transduction
GO:2001206
IDA
Genome Projectpositive regulation of osteoclast development

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005125
ISO
IEA
Genome Projectcytokine activity
GO:0005164
IEA
Genome Projecttumor necrosis factor receptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0032813
IPI
Genome Projecttumor necrosis factor receptor superfamily binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005615
IEA
Genome Projectextracellular space
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005886
IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR006052Tumour necrosis factor domain
IPR008983Tumour necrosis factor-like domain
IPR017355Tumour necrosis factor ligand 10/11

No MapMan annotations defined for this gene.