Gene: ENSMUSG00000021871 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000021871
Transcript Identifier
ENSMUST00000178092
Gene Type
Coding gene
Location
14 : 50944583-50951621 : positive

Family Information

Homologous gene family
HOM03P006024
(15 genes in 11 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
purine-nucleoside phosphorylase

Identifiers

Type Value
UniprotQ543K9
MGI97365

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001916
IMP
Genome Projectpositive regulation of T cell mediated cytotoxicity
GO:0006139
IEA
Genome Projectnucleobase-containing compound metabolic process
GO:0006148
IMP
ISO
Genome Projectinosine catabolic process
GO:0006149
IMP
Genome Projectdeoxyinosine catabolic process
GO:0006161
IMP
Genome Projectdeoxyguanosine catabolic process
GO:0006183
IMP
Genome ProjectGTP biosynthetic process
GO:0008630
IMP
Genome Projectintrinsic apoptotic signaling pathway in response to DNA damage
GO:0008637
IMP
Genome Projectapoptotic mitochondrial changes
GO:0009116
IEA
Genome Projectnucleoside metabolic process
GO:0010332
IMP
Genome Projectresponse to gamma radiation
GO:0034418
IMP
ISO
Genome Projecturate biosynthetic process
GO:0042102
IMP
ISO
Genome Projectpositive regulation of T cell proliferation
GO:0042278
IDA, IMP
IC
Genome Projectpurine nucleoside metabolic process
GO:0043101
IBA
Genome Projectpurine-containing compound salvage
GO:0045579
IMP
Genome Projectpositive regulation of B cell differentiation
GO:0045739
IMP
Genome Projectpositive regulation of DNA repair
GO:0046070
IMP
Genome ProjectdGTP metabolic process
GO:0046115
IMP
Genome Projectguanosine catabolic process
GO:0046638
IMP
ISO
Genome Projectpositive regulation of alpha-beta T cell differentiation
GO:0070233
IMP
Genome Projectnegative regulation of T cell apoptotic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001882
ISO
Genome Projectnucleoside binding
GO:0002060
ISO
Genome Projectpurine nucleobase binding
GO:0003824
IEA
Genome Projectcatalytic activity
GO:0004731
IDA, IMP
ISO
IEA
Genome Projectpurine-nucleoside phosphorylase activity
GO:0008144
ISO
Genome Projectdrug binding
GO:0016740
IEA
Genome Projecttransferase activity
GO:0016757
IEA
Genome Projecttransferase activity, transferring glycosyl groups
GO:0016763
IEA
Genome Projecttransferase activity, transferring pentosyl groups
GO:0042301
ISO
Genome Projectphosphate ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
ISO
Genome Projectintracellular
GO:0005737
ISO, IBA
Genome Projectcytoplasm
GO:0005829
IDA
Genome Projectcytosol
GO:0070062
ISO
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000845Nucleoside phosphorylase domain
IPR001369PNP/MTAP phosphorylase
IPR011268Purine nucleoside phosphorylase
IPR011270Purine nucleoside phosphorylase I, inosine/guanosine-specific
IPR018099Purine phosphorylase, family 2, conserved site

No MapMan annotations defined for this gene.