Gene: ENSMUSG00000021868 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000021868
Transcript Identifier
ENSMUST00000022419
Gene Type
Coding gene
Location
14 : 25694232-25699602 : positive

Family Information

Homologous gene family
HOM03P000030
(748 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P002540
(29 genes in 19 species)
specific family

Descriptions

gene_descr
peptidylprolyl isomerase F (cyclophilin F)

Identifiers

Type Value
UniprotQ99KR7
MGI2145814

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000413
TAS, IEA
Genome Projectprotein peptidyl-prolyl isomerization
GO:0002931
IMP
Genome Projectresponse to ischemia
GO:0006457
IEA
Genome Projectprotein folding
GO:0006915
IEA
Genome Projectapoptotic process
GO:0006979
IGI
Genome Projectresponse to oxidative stress
GO:0008637
IGI
Genome Projectapoptotic mitochondrial changes
GO:0010849
IMP
Genome Projectregulation of proton-transporting ATPase activity, rotational mechanism
GO:0010939
IDA
Genome Projectregulation of necrotic cell death
GO:0012501
IEA
Genome Projectprogrammed cell death
GO:0032780
IMP
Genome Projectnegative regulation of ATPase activity
GO:0042981
IEA
Genome Projectregulation of apoptotic process
GO:0043066
ISS, ISO
IEA
Genome Projectnegative regulation of apoptotic process
GO:0046902
IMP, IGI
IEA
Genome Projectregulation of mitochondrial membrane permeability
GO:0070266
IGI
Genome Projectnecroptotic process
GO:0070301
IMP
ISO
IEA
Genome Projectcellular response to hydrogen peroxide
GO:0071243
IMP
Genome Projectcellular response to arsenic-containing substance
GO:0071277
IMP
Genome Projectcellular response to calcium ion
GO:0090200
IMP
Genome Projectpositive regulation of release of cytochrome c from mitochondria
GO:0090201
ISS, ISO
IEA
Genome Projectnegative regulation of release of cytochrome c from mitochondria
GO:0090324
IMP
Genome Projectnegative regulation of oxidative phosphorylation
GO:1902445
IMP
ISO
IEA
Genome Projectregulation of mitochondrial membrane permeability involved in programmed necrotic cell death
GO:2000276
IMP
Genome Projectnegative regulation of oxidative phosphorylation uncoupler activity
GO:2001243
ISS, ISO
IEA
Genome Projectnegative regulation of intrinsic apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003755
TAS, IEA
Genome Projectpeptidyl-prolyl cis-trans isomerase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0016018
IEA
Genome Projectcyclosporin A binding
GO:0016853
IEA
Genome Projectisomerase activity
GO:0042277
IEA
Genome Projectpeptide binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
IDA
IEA
Genome Projectmitochondrion
GO:0005743
IEA
Genome Projectmitochondrial inner membrane
GO:0005757
TAS
Genome Projectmitochondrial permeability transition pore complex
GO:0005759
IBA
IEA
Genome Projectmitochondrial matrix
GO:0005753
ISS
Genome Projectmitochondrial proton-transporting ATP synthase complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002130Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
IPR020892Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
IPR024936Cyclophilin-type peptidyl-prolyl cis-trans isomerase
IPR029000Cyclophilin-like domain

No MapMan annotations defined for this gene.