Gene: ENSMUSG00000021732 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000021732
Transcript Identifier
ENSMUST00000022246
Gene Type
Coding gene
Location
13 : 118715384-118789316 : positive

Family Information

Homologous gene family
HOM03P003461
(28 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P038858
(3 genes in 3 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
fibroblast growth factor 10

Identifiers

Type Value
UniprotO35565
MGI1099809

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000132
IGI
Genome Projectestablishment of mitotic spindle orientation
GO:0000187
ISO
IEA
Genome Projectactivation of MAPK activity
GO:0001525
IEA
Genome Projectangiogenesis
GO:0001656
IEA
Genome Projectmetanephros development
GO:0001759
IGI
ISO
IEA
Genome Projectorgan induction
GO:0001823
IEA
Genome Projectmesonephros development
GO:0001974
IGI
Genome Projectblood vessel remodeling
GO:0003338
IMP
Genome Projectmetanephros morphogenesis
GO:0006935
IDA
Genome Projectchemotaxis
GO:0007267
IDA, IMP
Genome Projectcell-cell signaling
GO:0007368
IMP
Genome Projectdetermination of left/right symmetry
GO:0007431
ISO
IEA
Genome Projectsalivary gland development
GO:0007435
IMP
Genome Projectsalivary gland morphogenesis
GO:0008284
IDA
Genome Projectpositive regulation of cell proliferation
GO:0008285
IDA
Genome Projectnegative regulation of cell proliferation
GO:0008543
IEA
Genome Projectfibroblast growth factor receptor signaling pathway
GO:0008544
IMP
Genome Projectepidermis development
GO:0008589
IMP
Genome Projectregulation of smoothened signaling pathway
GO:0009880
IMP
Genome Projectembryonic pattern specification
GO:0009887
IDA, IMP
Genome Projectorgan morphogenesis
GO:0010468
IMP
Genome Projectregulation of gene expression
GO:0010631
IMP
Genome Projectepithelial cell migration
GO:0010634
IDA
ISO
IEA
Genome Projectpositive regulation of epithelial cell migration
GO:0010838
ISO
IEA
Genome Projectpositive regulation of keratinocyte proliferation
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0021983
IMP
Genome Projectpituitary gland development
GO:0030154
IEA
Genome Projectcell differentiation
GO:0030177
IMP
Genome Projectpositive regulation of Wnt signaling pathway
GO:0030324
IDA, IMP
Genome Projectlung development
GO:0030538
IMP
Genome Projectembryonic genitalia morphogenesis
GO:0030855
IMP
Genome Projectepithelial cell differentiation
GO:0030878
IMP
Genome Projectthyroid gland development
GO:0030916
IGI
Genome Projectotic vesicle formation
GO:0030949
IMP
Genome Projectpositive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0031016
IMP
Genome Projectpancreas development
GO:0031069
IMP
Genome Projecthair follicle morphogenesis
GO:0031076
IMP
Genome Projectembryonic camera-type eye development
GO:0031532
ISO
IEA
Genome Projectactin cytoskeleton reorganization
GO:0031659
ISO
IEA
Genome Projectpositive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
GO:0032355
IEA
Genome Projectresponse to estradiol
GO:0032496
IEA
Genome Projectresponse to lipopolysaccharide
GO:0032781
ISO
IEA
Genome Projectpositive regulation of ATPase activity
GO:0032808
IMP
ISO
IEA
Genome Projectlacrimal gland development
GO:0032925
IMP
Genome Projectregulation of activin receptor signaling pathway
GO:0034394
ISO
IEA
Genome Projectprotein localization to cell surface
GO:0035019
IMP
Genome Projectsomatic stem cell population maintenance
GO:0035108
IMP
Genome Projectlimb morphogenesis
GO:0035265
IMP
Genome Projectorgan growth
GO:0042060
ISO
IEA
Genome Projectwound healing
GO:0042246
IEA
Genome Projecttissue regeneration
GO:0042472
IMP, IGI
Genome Projectinner ear morphogenesis
GO:0042475
IMP
Genome Projectodontogenesis of dentin-containing tooth
GO:0042693
IMP
Genome Projectmuscle cell fate commitment
GO:0043410
ISO
IEA
Genome Projectpositive regulation of MAPK cascade
GO:0043616
IMP
Genome Projectkeratinocyte proliferation
GO:0045596
IDA
Genome Projectnegative regulation of cell differentiation
GO:0045739
ISO
IEA
Genome Projectpositive regulation of DNA repair
GO:0045740
ISO
IEA
Genome Projectpositive regulation of DNA replication
GO:0045747
IGI
Genome Projectpositive regulation of Notch signaling pathway
GO:0045893
IDA
ISO
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045931
IMP
Genome Projectpositive regulation of mitotic cell cycle
GO:0045944
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046579
ISO
IEA
Genome Projectpositive regulation of Ras protein signal transduction
GO:0046877
ISO
IEA
Genome Projectregulation of saliva secretion
GO:0048146
IMP
Genome Projectpositive regulation of fibroblast proliferation
GO:0048286
IMP, IGI
Genome Projectlung alveolus development
GO:0048514
IMP
Genome Projectblood vessel morphogenesis
GO:0048536
IMP
Genome Projectspleen development
GO:0048538
ISO
IEA
Genome Projectthymus development
GO:0048557
IMP
Genome Projectembryonic digestive tract morphogenesis
GO:0048565
IMP
Genome Projectdigestive tract development
GO:0048566
IMP
Genome Projectembryonic digestive tract development
GO:0048645
IMP
Genome Projectorgan formation
GO:0048730
IMP
Genome Projectepidermis morphogenesis
GO:0048752
IGI
Genome Projectsemicircular canal morphogenesis
GO:0048754
ISO
IEA
Genome Projectbranching morphogenesis of an epithelial tube
GO:0048807
IMP
Genome Projectfemale genitalia morphogenesis
GO:0048808
IMP
Genome Projectmale genitalia morphogenesis
GO:0050671
ISO
IEA
Genome Projectpositive regulation of lymphocyte proliferation
GO:0050673
IMP
ISO
IEA
Genome Projectepithelial cell proliferation
GO:0050674
ISO
IEA
Genome Projecturothelial cell proliferation
GO:0050677
ISO
IEA
Genome Projectpositive regulation of urothelial cell proliferation
GO:0050678
IMP
Genome Projectregulation of epithelial cell proliferation
GO:0050679
IMP
ISO
IEA
Genome Projectpositive regulation of epithelial cell proliferation
GO:0050731
ISO
IEA
Genome Projectpositive regulation of peptidyl-tyrosine phosphorylation
GO:0050872
IMP
Genome Projectwhite fat cell differentiation
GO:0050918
IDA
ISO
IEA
Genome Projectpositive chemotaxis
GO:0050930
IDA
Genome Projectinduction of positive chemotaxis
GO:0051145
IMP
Genome Projectsmooth muscle cell differentiation
GO:0051549
ISO
IEA
Genome Projectpositive regulation of keratinocyte migration
GO:0060019
IMP
Genome Projectradial glial cell differentiation
GO:0060173
IMP
Genome Projectlimb development
GO:0060174
IMP
Genome Projectlimb bud formation
GO:0060425
IMP
Genome Projectlung morphogenesis
GO:0060428
ISO
IEA
Genome Projectlung epithelium development
GO:0060430
ISO
IEA
Genome Projectlung saccule development
GO:0060436
IMP
Genome Projectbronchiole morphogenesis
GO:0060441
IDA, IMP
Genome Projectepithelial tube branching involved in lung morphogenesis
GO:0060445
IDA, IGI
Genome Projectbranching involved in salivary gland morphogenesis
GO:0060447
ISO
IEA
Genome Projectbud outgrowth involved in lung branching
GO:0060449
IGI
Genome Projectbud elongation involved in lung branching
GO:0060496
IDA
Genome Projectmesenchymal-epithelial cell signaling involved in lung development
GO:0060510
IDA
Genome ProjectType II pneumocyte differentiation
GO:0060513
IGI
Genome Projectprostatic bud formation
GO:0060541
IDA
Genome Projectrespiratory system development
GO:0060594
IGI
Genome Projectmammary gland specification
GO:0060595
IDA, IMP
ISO
IEA
Genome Projectfibroblast growth factor receptor signaling pathway involved in mammary gland specification
GO:0060615
IMP
Genome Projectmammary gland bud formation
GO:0060661
IMP
Genome Projectsubmandibular salivary gland formation
GO:0060664
IMP, IGI
Genome Projectepithelial cell proliferation involved in salivary gland morphogenesis
GO:0060665
IDA
Genome Projectregulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
GO:0060667
IMP
Genome Projectbranch elongation involved in salivary gland morphogenesis
GO:0060879
IMP
Genome Projectsemicircular canal fusion
GO:0060915
IGI
Genome Projectmesenchymal cell differentiation involved in lung development
GO:0061033
ISO
IEA
Genome Projectsecretion by lung epithelial cell involved in lung growth
GO:0061115
IDA
Genome Projectlung proximal/distal axis specification
GO:0070075
ISO
IEA
Genome Projecttear secretion
GO:0070352
IMP
Genome Projectpositive regulation of white fat cell proliferation
GO:0070371
ISO
IEA
Genome ProjectERK1 and ERK2 cascade
GO:0070374
IMP, IGI
ISO
IEA
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0070384
IMP
Genome ProjectHarderian gland development
GO:0071157
ISO
IEA
Genome Projectnegative regulation of cell cycle arrest
GO:0071338
ISO
IEA
Genome Projectpositive regulation of hair follicle cell proliferation
GO:0090263
IMP
Genome Projectpositive regulation of canonical Wnt signaling pathway
GO:2001240
IMP
Genome Projectnegative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005102
IEA
Genome Projectreceptor binding
GO:0005104
ISO
IEA
Genome Projectfibroblast growth factor receptor binding
GO:0005111
ISO
IEA
Genome Projecttype 2 fibroblast growth factor receptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008083
ISO
IEA
Genome Projectgrowth factor activity
GO:0008201
ISO
IEA
Genome Projectheparin binding
GO:0042056
IDA
ISO
IEA
Genome Projectchemoattractant activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005615
IDA
ISO
IEA
Genome Projectextracellular space
GO:0005634
ISO
IEA
Genome Projectnucleus
GO:0005886
ISO
IEA
Genome Projectplasma membrane
GO:0009986
ISO
Genome Projectcell surface
GO:0031012
ISO
IEA
Genome Projectextracellular matrix

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002209Fibroblast growth factor family
IPR008996Cytokine, IL-1-like
IPR028142IL-1 family/FGF family
IPR028252Fibroblast growth factor 10

No MapMan annotations defined for this gene.