Gene: ENSMUSG00000021678 (Mus musculus)

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Gene Identifier
ENSMUSG00000021678
Transcript Identifier
ENSMUST00000022185
Gene Type
Coding gene
Location
13 : 95513173-95525127 : negative

Family Information

Homologous gene family
HOM03P000080
(330 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P073622
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
coagulation factor II (thrombin) receptor-like 1

Identifiers

Type Value
UniprotP55086
UniprotQ3TU81
MGI101910

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002286
IDA
Genome ProjectT cell activation involved in immune response
GO:0002376
IEA
Genome Projectimmune system process
GO:0002690
ISO
IEA
Genome Projectpositive regulation of leukocyte chemotaxis
GO:0002741
ISS, ISO
IEA
Genome Projectpositive regulation of cytokine secretion involved in immune response
GO:0003104
ISS
IEA
Genome Projectpositive regulation of glomerular filtration
GO:0006954
IEA
Genome Projectinflammatory response
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007186
IEA
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007204
IDA
ISO
Genome Projectpositive regulation of cytosolic calcium ion concentration
GO:0007596
IEA
Genome Projectblood coagulation
GO:0010804
ISO
IEA
Genome Projectnegative regulation of tumor necrosis factor-mediated signaling pathway
GO:0014068
IDA
Genome Projectpositive regulation of phosphatidylinositol 3-kinase signaling
GO:0030193
ISO
IEA
Genome Projectregulation of blood coagulation
GO:0030335
IDA
Genome Projectpositive regulation of cell migration
GO:0030836
ISO
IEA
Genome Projectpositive regulation of actin filament depolymerization
GO:0031274
IDA
Genome Projectpositive regulation of pseudopodium assembly
GO:0032930
ISS, ISO
IEA
Genome Projectpositive regulation of superoxide anion generation
GO:0034137
ISO
IEA
Genome Projectpositive regulation of toll-like receptor 2 signaling pathway
GO:0034140
ISO
IEA
Genome Projectnegative regulation of toll-like receptor 3 signaling pathway
GO:0034141
ISO
IEA
Genome Projectpositive regulation of toll-like receptor 3 signaling pathway
GO:0034145
ISO
IEA
Genome Projectpositive regulation of toll-like receptor 4 signaling pathway
GO:0035025
IDA
ISO
Genome Projectpositive regulation of Rho protein signal transduction
GO:0035926
ISS, ISO
IEA
Genome Projectchemokine (C-C motif) ligand 2 secretion
GO:0042119
ISS, ISO
IEA
Genome Projectneutrophil activation
GO:0043122
ISS, ISO
IEA
Genome Projectregulation of I-kappaB kinase/NF-kappaB signaling
GO:0043123
ISS, ISO
IEA
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043311
ISO
IEA
Genome Projectpositive regulation of eosinophil degranulation
GO:0045087
IEA
Genome Projectinnate immune response
GO:0045909
IDA, IMP
IEA
Genome Projectpositive regulation of vasodilation
GO:0045944
ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046328
ISS, ISO
IEA
Genome Projectregulation of JNK cascade
GO:0046329
ISO
IEA
Genome Projectnegative regulation of JNK cascade
GO:0046330
ISO
IEA
Genome Projectpositive regulation of JNK cascade
GO:0050702
ISS, ISO
IEA
Genome Projectinterleukin-1 beta secretion
GO:0050900
ISS, ISO
IEA
Genome Projectleukocyte migration
GO:0050921
IDA
Genome Projectpositive regulation of chemotaxis
GO:0050927
ISO
IEA
Genome Projectpositive regulation of positive chemotaxis
GO:0051607
IDA
ISO
IEA
Genome Projectdefense response to virus
GO:0060100
ISO
IEA
Genome Projectpositive regulation of phagocytosis, engulfment
GO:0061028
ISO
IEA
Genome Projectestablishment of endothelial barrier
GO:0070374
IDA
ISO
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0070493
IEA
Genome Projectthrombin receptor signaling pathway
GO:0070661
IDA
Genome Projectleukocyte proliferation
GO:0070963
ISO
IEA
Genome Projectpositive regulation of neutrophil mediated killing of gram-negative bacterium
GO:0072608
ISS, ISO
IEA
Genome Projectinterleukin-10 secretion
GO:0072643
IDA
Genome Projectinterferon-gamma secretion
GO:0090195
IDA
ISO
IEA
Genome Projectchemokine secretion
GO:0090198
ISO
IEA
Genome Projectnegative regulation of chemokine secretion
GO:0097029
IDA
ISO
Genome Projectmature conventional dendritic cell differentiation
GO:1900135
IDA
Genome Projectpositive regulation of renin secretion into blood stream
GO:2000484
ISS, ISO
IEA
Genome Projectpositive regulation of interleukin-8 secretion
GO:2000778
ISS, ISO
IEA
Genome Projectpositive regulation of interleukin-6 secretion

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001965
IDA
Genome ProjectG-protein alpha-subunit binding
GO:0004871
IEA
Genome Projectsignal transducer activity
GO:0004930
IMP
ISO
IEA
Genome ProjectG-protein coupled receptor activity
GO:0015057
IEA
Genome Projectthrombin receptor activity
GO:0031681
IDA
Genome ProjectG-protein beta-subunit binding
GO:0032795
TAS
Genome Projectheterotrimeric G-protein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005769
ISO
IEA
Genome Projectearly endosome
GO:0005829
ISO
Genome Projectcytosol
GO:0005886
ISO
IEA
Genome Projectplasma membrane
GO:0005887
ISO
IEA
Genome Projectintegral component of plasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0031143
IDA
Genome Projectpseudopodium

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000276G protein-coupled receptor, rhodopsin-like
IPR002281Protease-activated receptor 2
IPR003912Protease-activated receptor
IPR017452GPCR, rhodopsin-like, 7TM

No MapMan annotations defined for this gene.