Gene: ENSMUSG00000021676 (Mus musculus)

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Gene Identifier
ENSMUSG00000021676
Transcript Identifier
ENSMUST00000068603
Gene Type
Coding gene
Location
13 : 95628007-95891709 : negative

Family Information

Homologous gene family
HOM03P007040
(12 genes in 6 species)
specific family
Orthologous gene family
ORTHO03P009182
(9 genes in 6 species)
specific family

Descriptions

gene_descr
IQ motif containing GTPase activating protein 2

Identifiers

Type Value
UniprotQ3UQ44
MGI2449975

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007165
IEA
Genome Projectsignal transduction
GO:0007264
IEA
Genome Projectsmall GTPase mediated signal transduction
GO:0034314
ISO
IEA
Genome ProjectArp2/3 complex-mediated actin nucleation
GO:0043087
IEA
Genome Projectregulation of GTPase activity
GO:0043547
IEA
Genome Projectpositive regulation of GTPase activity
GO:0070493
ISO
IEA
Genome Projectthrombin receptor signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005096
IEA
Genome ProjectGTPase activator activity
GO:0005516
ISO
IEA
Genome Projectcalmodulin binding
GO:0005547
ISS, ISO
IEA
Genome Projectphosphatidylinositol-3,4,5-trisphosphate binding
GO:0017048
ISO
IEA
Genome ProjectRho GTPase binding
GO:0048365
ISO
IEA
Genome ProjectRac GTPase binding
GO:0051015
ISO
IEA
Genome Projectactin filament binding
GO:0071933
ISO
IEA
Genome ProjectArp2/3 complex binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0005874
ISO
IEA
Genome Projectmicrotubule
GO:0005902
IDA
Genome Projectmicrovillus
GO:0009986
ISO
IEA
Genome Projectcell surface
GO:0030027
ISO
IEA
Genome Projectlamellipodium
GO:0030175
ISO
IEA
Genome Projectfilopodium
GO:0031941
ISO
IEA
Genome Projectfilamentous actin
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000048IQ motif, EF-hand binding site
IPR000593RasGAP protein, C-terminal
IPR001202WW domain
IPR001715Calponin homology domain
IPR001936Ras GTPase-activating protein
IPR008936Rho GTPase activation protein
IPR023152Ras GTPase-activating protein, conserved site

No MapMan annotations defined for this gene.