Gene: ENSMUSG00000021477 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000021477
Transcript Identifier
ENSMUST00000021933
Gene Type
Coding gene
Location
13 : 64364098-64369153 : negative

Family Information

Homologous gene family
HOM03P000044
(550 genes in 34 species)
specific family
Orthologous gene family
ORTHO03P000333
(54 genes in 32 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
cathepsin L

Identifiers

Type Value
UniprotP06797
UniprotQ543M3
MGI88564

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006508
IDA
ISS
IEA
Genome Projectproteolysis
GO:0007154
ISS
IEA
Genome Projectcell communication
GO:0007283
ISS
IEA
Genome Projectspermatogenesis
GO:0008584
ISS
IEA
Genome Projectmale gonad development
GO:0009267
ISS
IEA
Genome Projectcellular response to starvation
GO:0009749
ISS
IEA
Genome Projectresponse to glucose
GO:0010259
ISS
IEA
Genome Projectmulticellular organismal aging
GO:0010839
IMP
Genome Projectnegative regulation of keratinocyte proliferation
GO:0014070
ISS
IEA
Genome Projectresponse to organic cyclic compound
GO:0016485
IDA, IMP
Genome Projectprotein processing
GO:0016540
IDA
Genome Projectprotein autoprocessing
GO:0021675
ISS
IEA
Genome Projectnerve development
GO:0031069
IMP
Genome Projecthair follicle morphogenesis
GO:0034698
ISS
IEA
Genome Projectresponse to gonadotropin
GO:0046697
IGI
ISS
IEA
Genome Projectdecidualization
GO:0048102
ISS
IEA
Genome Projectautophagic cell death
GO:0051384
ISS
IEA
Genome Projectresponse to glucocorticoid
GO:0051603
IBA
Genome Projectproteolysis involved in cellular protein catabolic process
GO:0060008
ISS
IEA
Genome ProjectSertoli cell differentiation
GO:2000249
IGI
Genome Projectregulation of actin cytoskeleton reorganization
GO:0060441
IMP
Genome Projectepithelial tube branching involved in lung morphogenesis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004177
ISS
IEA
Genome Projectaminopeptidase activity
GO:0004197
ISS, IBA
IEA
Genome Projectcysteine-type endopeptidase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008233
IEA
Genome Projectpeptidase activity
GO:0008234
IEA
Genome Projectcysteine-type peptidase activity
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0016807
IDA
Genome Projectcysteine-type carboxypeptidase activity
GO:0030984
IEA
Genome Projectkininogen binding
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0042277
ISS
IEA
Genome Projectpeptide binding
GO:0042393
IDA
Genome Projecthistone binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005615
IDA
Genome Projectextracellular space
GO:0005634
IDA
Genome Projectnucleus
GO:0005730
IDA
Genome Projectnucleolus
GO:0005737
ISS
IEA
Genome Projectcytoplasm
GO:0005764
IDA
ISS
IEA
Genome Projectlysosome
GO:0005773
ISS
IEA
Genome Projectvacuole
GO:0005902
ISS
IEA
Genome Projectmicrovillus
GO:0009897
ISS
IEA
Genome Projectexternal side of plasma membrane
GO:0030141
ISS
IEA
Genome Projectsecretory granule
GO:0031410
IDA
Genome Projectcytoplasmic vesicle
GO:0043005
ISS
IEA
Genome Projectneuron projection
GO:0043204
ISS
IEA
Genome Projectperikaryon
GO:0045177
ISS
IEA
Genome Projectapical part of cell
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000169Cysteine peptidase, cysteine active site
IPR000668Peptidase C1A, papain C-terminal
IPR013128Peptidase C1A
IPR013201Cathepsin propeptide inhibitor domain (I29)
IPR025660Cysteine peptidase, histidine active site
IPR025661Cysteine peptidase, asparagine active site

No MapMan annotations defined for this gene.