Gene: ENSMUSG00000021214 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000021214
Transcript Identifier
ENSMUST00000021635
Gene Type
Coding gene
Location
13 : 4132794-4150598 : negative

Family Information

Homologous gene family
HOM03P000087
(311 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P017638
(5 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
aldo-keto reductase family 1, member C18

Identifiers

Type Value
UniprotQ8K023
UniprotQ3U538
MGI2145420

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000060
ISO
Genome Projectprotein import into nucleus, translocation
GO:0006709
IDA, IMP
Genome Projectprogesterone catabolic process
GO:0007186
ISO
Genome ProjectG-protein coupled receptor signaling pathway
GO:0007567
IMP
Genome Projectparturition
GO:0008284
ISO
Genome Projectpositive regulation of cell proliferation
GO:0010942
ISO
Genome Projectpositive regulation of cell death
GO:0016488
ISO
Genome Projectfarnesol catabolic process
GO:0034614
ISO
Genome Projectcellular response to reactive oxygen species
GO:0042448
ISO
IEA
Genome Projectprogesterone metabolic process
GO:0042574
ISO
Genome Projectretinal metabolic process
GO:0044597
ISO
Genome Projectdaunorubicin metabolic process
GO:0044598
ISO
Genome Projectdoxorubicin metabolic process
GO:0048385
ISO
Genome Projectregulation of retinoic acid receptor signaling pathway
GO:0050810
IEA
Genome Projectregulation of steroid biosynthetic process
GO:0051897
ISO
Genome Projectpositive regulation of protein kinase B signaling
GO:0055114
ISO
IEA
Genome Projectoxidation-reduction process
GO:0061370
ISO
Genome Projecttestosterone biosynthetic process
GO:0071276
ISO
Genome Projectcellular response to cadmium ion
GO:0071277
ISO
Genome Projectcellular response to calcium ion
GO:0071379
ISO
Genome Projectcellular response to prostaglandin stimulus
GO:0071384
ISO
Genome Projectcellular response to corticosteroid stimulus
GO:0071395
ISO
Genome Projectcellular response to jasmonic acid stimulus
GO:0071799
ISO
Genome Projectcellular response to prostaglandin D stimulus
GO:1900053
ISO
Genome Projectnegative regulation of retinoic acid biosynthetic process
GO:2000224
ISO
Genome Projectregulation of testosterone biosynthetic process
GO:2000353
ISO
Genome Projectpositive regulation of endothelial cell apoptotic process
GO:2000379
ISO
Genome Projectpositive regulation of reactive oxygen species metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001758
ISO
Genome Projectretinal dehydrogenase activity
GO:0004032
ISO
Genome Projectalditol:NADP+ 1-oxidoreductase activity
GO:0004745
ISO
Genome Projectretinol dehydrogenase activity
GO:0016491
IEA
Genome Projectoxidoreductase activity
GO:0016655
ISO
Genome Projectoxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO:0018636
ISO
Genome Projectphenanthrene 9,10-monooxygenase activity
GO:0035410
ISO
Genome Projectdihydrotestosterone 17-beta-dehydrogenase activity
GO:0045550
ISO
Genome Projectgeranylgeranyl reductase activity
GO:0045703
ISO
Genome Projectketoreductase activity
GO:0047006
IDA, IMP
ISO
IEA
Genome Project17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
GO:0047020
ISO
Genome Project15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity
GO:0047023
ISO
Genome Projectandrosterone dehydrogenase activity
GO:0047086
ISO
Genome Projectketosteroid monooxygenase activity
GO:0047787
ISO
Genome Projectdelta4-3-oxosteroid 5beta-reductase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005622
ISO
Genome Projectintracellular
GO:0005634
ISO
Genome Projectnucleus
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0005829
ISO
IEA
Genome Projectcytosol
GO:0070062
ISO
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001395Aldo/keto reductase/potassium channel subunit beta
IPR018170Aldo/keto reductase, conserved site
IPR020471Aldo/keto reductase
IPR023210NADP-dependent oxidoreductase domain

No MapMan annotations defined for this gene.