Gene: ENSMUSG00000021116 (Mus musculus)

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Gene Identifier
ENSMUSG00000021116
Transcript Identifier
ENSMUST00000071230
Gene Type
Coding gene
Location
12 : 78866527-78884916 : positive

Family Information

Homologous gene family
HOM03P001598
(48 genes in 37 species)
specific family

Descriptions

gene_descr
eukaryotic translation initiation factor 2, subunit 1 alpha

Identifiers

Type Value
UniprotQ6ZWX6
MGI95299

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002230
ISO
Genome Projectpositive regulation of defense response to virus by host
GO:0006412
IDA
IEA
Genome Projecttranslation
GO:0006413
IBA
IEA
Genome Projecttranslational initiation
GO:0006417
IEA
Genome Projectregulation of translation
GO:0043558
IDA
Genome Projectregulation of translational initiation in response to stress
GO:0046777
IDA
Genome Projectprotein autophosphorylation
GO:0098779
ISO
Genome Projectmitophagy in response to mitochondrial depolarization
GO:1903146
IEA
Genome Projectregulation of mitophagy

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003676
IEA
Genome Projectnucleic acid binding
GO:0003723
IEA
Genome ProjectRNA binding
GO:0003743
ISS, ISO, IBA
IEA
Genome Projecttranslation initiation factor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0043022
ISS, ISO, IBA
IEA
Genome Projectribosome binding
GO:0044822
ISO, IBA
IEA
Genome Projectpoly(A) RNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
Genome Projectnucleus
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005840
IBA
Genome Projectribosome
GO:0005850
IBA
IEA
Genome Projecteukaryotic translation initiation factor 2 complex
GO:0005851
ISS, ISO, IBA
IEA
Genome Projecteukaryotic translation initiation factor 2B complex
GO:0010494
IDA
Genome Projectcytoplasmic stress granule
GO:0016020
ISO
IEA
Genome Projectmembrane
GO:0033290
IBA
Genome Projecteukaryotic 48S preinitiation complex
GO:0043614
IBA
Genome Projectmulti-eIF complex
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003029S1 domain
IPR011488Translation initiation factor 2, alpha subunit
IPR012340Nucleic acid-binding, OB-fold
IPR022967RNA-binding domain, S1
IPR024054Translation initiation factor 2, alpha subunit, middle domain
IPR024055Translation initiation factor 2, alpha subunit, C-terminal

No MapMan annotations defined for this gene.