Gene: ENSMUSG00000021108 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000021108
Transcript Identifier
ENSMUST00000021527
Gene Type
Coding gene
Location
12 : 73585163-73777058 : positive

Family Information

Homologous gene family
HOM03P000015
(1237 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P005549
(15 genes in 6 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
protein kinase C, eta

Identifiers

Type Value
UniprotP23298
MGI97600

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006468
ISS, ISO
IEA
Genome Projectprotein phosphorylation
GO:0010744
IMP
Genome Projectpositive regulation of macrophage derived foam cell differentiation
GO:0016310
IEA
Genome Projectphosphorylation
GO:0030154
IEA
Genome Projectcell differentiation
GO:0034351
ISS, ISO
IEA
Genome Projectnegative regulation of glial cell apoptotic process
GO:0035556
IEA
Genome Projectintracellular signal transduction
GO:0045618
IMP
Genome Projectpositive regulation of keratinocyte differentiation
GO:0050861
ISS, ISO
IEA
Genome Projectpositive regulation of B cell receptor signaling pathway
GO:0051092
ISS, ISO
IEA
Genome Projectpositive regulation of NF-kappaB transcription factor activity
GO:0060252
ISS, ISO
IEA
Genome Projectpositive regulation of glial cell proliferation
GO:0070528
IEA
Genome Projectprotein kinase C signaling
GO:2000810
ISS, ISO
IEA
Genome Projectregulation of bicellular tight junction assembly

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004674
IEA
Genome Projectprotein serine/threonine kinase activity
GO:0004697
IEA
Genome Projectprotein kinase C activity
GO:0004699
IEA
Genome Projectcalcium-independent protein kinase C activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0017160
IPI
Genome ProjectRal GTPase binding
GO:0019899
ISO
IEA
Genome Projectenzyme binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0005829
IDA
IEA
Genome Projectcytosol
GO:0005886
IDA
ISO
IEA
Genome Projectplasma membrane
GO:0005911
IDA
Genome Projectcell-cell junction
GO:0016020
IEA
Genome Projectmembrane
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000008C2 domain
IPR000719Protein kinase domain
IPR000961AGC-kinase, C-terminal
IPR002219Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
IPR002290Serine/threonine/dual specificity protein kinase, catalytic domain
IPR008271Serine/threonine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR014376Protein kinase C, delta/epsilon/eta/theta types
IPR017441Protein kinase, ATP binding site
IPR017892Protein kinase, C-terminal
IPR020454Diacylglycerol/phorbol-ester binding
IPR027431Protein kinase C, eta

No MapMan annotations defined for this gene.