Gene: ENSMUSG00000021025 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000021025
Transcript Identifier
ENSMUST00000021413
Gene Type
Coding gene
Location
12 : 55489922-55492526 : negative

Family Information

Homologous gene family
HOM03P000010
(1560 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P042840
(3 genes in 3 species)
specific family

Descriptions

gene_descr
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha

Identifiers

Type Value
UniprotQ9Z1E3
MGI104741

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000060
IDA
Genome Projectprotein import into nucleus, translocation
GO:0007253
ISO
IEA
Genome Projectcytoplasmic sequestering of NF-kappaB
GO:0010468
IMP
Genome Projectregulation of gene expression
GO:0010745
ISO
IEA
Genome Projectnegative regulation of macrophage derived foam cell differentiation
GO:0010875
ISO
IEA
Genome Projectpositive regulation of cholesterol efflux
GO:0010888
ISO
IEA
Genome Projectnegative regulation of lipid storage
GO:0031663
IDA
Genome Projectlipopolysaccharide-mediated signaling pathway
GO:0032088
ISO
IEA
Genome Projectnegative regulation of NF-kappaB transcription factor activity
GO:0032270
ISO
IEA
Genome Projectpositive regulation of cellular protein metabolic process
GO:0032495
IDA
Genome Projectresponse to muramyl dipeptide
GO:0032496
IDA
Genome Projectresponse to lipopolysaccharide
GO:0034142
IDA
Genome Projecttoll-like receptor 4 signaling pathway
GO:0035994
IDA
Genome Projectresponse to muscle stretch
GO:0042127
IDA
Genome Projectregulation of cell proliferation
GO:0042994
ISO
IEA
Genome Projectcytoplasmic sequestering of transcription factor
GO:0043330
IDA
Genome Projectresponse to exogenous dsRNA
GO:0045638
IMP
Genome Projectnegative regulation of myeloid cell differentiation
GO:0045746
IMP
Genome Projectnegative regulation of Notch signaling pathway
GO:0045893
IMP
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0070427
IDA
Genome Projectnucleotide-binding oligomerization domain containing 1 signaling pathway
GO:0070431
IDA
Genome Projectnucleotide-binding oligomerization domain containing 2 signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Genome Projectprotein binding
GO:0008139
ISO
IEA
Genome Projectnuclear localization sequence binding
GO:0019899
ISO
IEA
Genome Projectenzyme binding
GO:0031072
IEA
Genome Projectheat shock protein binding
GO:0031625
ISO
IEA
Genome Projectubiquitin protein ligase binding
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0042802
ISO
IEA
Genome Projectidentical protein binding
GO:0051059
ISO
IEA
Genome ProjectNF-kappaB binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005737
IDA
ISO
IEA
Genome Projectcytoplasm
GO:0005829
IDA
IEA
Genome Projectcytosol
GO:0005886
ISO
IEA
Genome Projectplasma membrane
GO:0043234
IEA
Genome Projectprotein complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR002110Ankyrin repeat
IPR020683Ankyrin repeat-containing domain

No MapMan annotations defined for this gene.