Gene: ENSMUSG00000020689 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000020689
Transcript Identifier
ENSMUST00000021028
Gene Type
Coding gene
Location
11 : 104608089-104667145 : positive

Family Information

Homologous gene family
HOM03P005934
(15 genes in 4 species)
specific family

Descriptions

gene_descr
integrin beta 3

Identifiers

Type Value
UniprotO54890
MGI96612

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001938
ISO
Genome Projectpositive regulation of endothelial cell proliferation
GO:0006457
ISO
Genome Projectprotein folding
GO:0007044
IDA
IEA
Genome Projectcell-substrate junction assembly
GO:0007155
IEA
Genome Projectcell adhesion
GO:0007160
IGI
ISO
IEA
Genome Projectcell-matrix adhesion
GO:0007229
ISO
IEA
Genome Projectintegrin-mediated signaling pathway
GO:0010595
ISO
Genome Projectpositive regulation of endothelial cell migration
GO:0010745
ISO
Genome Projectnegative regulation of macrophage derived foam cell differentiation
GO:0010888
ISO
Genome Projectnegative regulation of lipid storage
GO:0014909
ISO
Genome Projectsmooth muscle cell migration
GO:0016049
ISO
Genome Projectcell growth
GO:0016477
ISO
Genome Projectcell migration
GO:0030168
ISO
Genome Projectplatelet activation
GO:0030334
IMP
IEA
Genome Projectregulation of cell migration
GO:0030335
IMP
Genome Projectpositive regulation of cell migration
GO:0031589
ISO
Genome Projectcell-substrate adhesion
GO:0032147
ISO
Genome Projectactivation of protein kinase activity
GO:0032369
ISO
Genome Projectnegative regulation of lipid transport
GO:0033690
IMP
Genome Projectpositive regulation of osteoblast proliferation
GO:0034113
ISO
Genome Projectheterotypic cell-cell adhesion
GO:0034446
ISO
Genome Projectsubstrate adhesion-dependent cell spreading
GO:0038027
ISO
Genome Projectapolipoprotein A-I-mediated signaling pathway
GO:0045672
IC
Genome Projectpositive regulation of osteoclast differentiation
GO:0045715
ISO
Genome Projectnegative regulation of low-density lipoprotein particle receptor biosynthetic process
GO:0045780
IC
Genome Projectpositive regulation of bone resorption
GO:0046718
ISO
Genome Projectviral entry into host cell
GO:0048858
IC
Genome Projectcell projection morphogenesis
GO:0050731
ISO
Genome Projectpositive regulation of peptidyl-tyrosine phosphorylation
GO:0050748
ISO
Genome Projectnegative regulation of lipoprotein metabolic process
GO:0050919
ISO
Genome Projectnegative chemotaxis
GO:0060055
IEA
Genome Projectangiogenesis involved in wound healing
GO:0070527
ISO
IEA
Genome Projectplatelet aggregation
GO:2000406
IDA
Genome Projectpositive regulation of T cell migration

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001968
ISO
Genome Projectfibronectin binding
GO:0002020
ISO
Genome Projectprotease binding
GO:0003756
ISO
Genome Projectprotein disulfide isomerase activity
GO:0004872
IEA
Genome Projectreceptor activity
GO:0005178
IPI
Genome Projectintegrin binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0019899
IPI
Genome Projectenzyme binding
GO:0042802
ISO
Genome Projectidentical protein binding
GO:0043184
ISO
Genome Projectvascular endothelial growth factor receptor 2 binding
GO:0050839
ISO
Genome Projectcell adhesion molecule binding
GO:0050840
ISO
Genome Projectextracellular matrix binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
ISO
Genome Projectnucleus
GO:0005886
ISO
IEA
Genome Projectplasma membrane
GO:0005925
ISO
IEA
Genome Projectfocal adhesion
GO:0008305
ISO
IEA
Genome Projectintegrin complex
GO:0009897
IDA
Genome Projectexternal side of plasma membrane
GO:0009986
IDA
ISO
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0016324
IDA
Genome Projectapical plasma membrane
GO:0030054
IEA
Genome Projectcell junction
GO:0031258
ISO
IEA
Genome Projectlamellipodium membrane
GO:0031527
ISO
Genome Projectfilopodium membrane
GO:0031528
ISO
Genome Projectmicrovillus membrane
GO:0032587
ISO
Genome Projectruffle membrane
GO:0034679
TAS
Genome Projectintegrin alpha9-beta1 complex
GO:0034683
ISO
Genome Projectintegrin alphav-beta3 complex
GO:0042470
ISO
Genome Projectmelanosome
GO:0042995
IEA
Genome Projectcell projection
GO:0043235
ISO
Genome Projectreceptor complex
GO:0070062
ISO
Genome Projectextracellular exosome
GO:0071133
IDA
Genome Projectalpha9-beta1 integrin-ADAM8 complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002035von Willebrand factor, type A
IPR002369Integrin beta subunit, N-terminal
IPR012896Integrin beta subunit, tail
IPR013111EGF-like domain, extracellular
IPR014836Integrin beta subunit, cytoplasmic domain
IPR015812Integrin beta subunit
IPR016201Plexin-like fold
IPR027068Integrin beta-3 subunit

No MapMan annotations defined for this gene.