Gene: ENSMUSG00000020661 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000020661
Transcript Identifier
ENSMUST00000174817
Gene Type
Coding gene
Location
12 : 3835198-3907747 : positive

Family Information

Homologous gene family
HOM03P007594
(11 genes in 6 species)
specific family
Orthologous gene family
ORTHO03P022893
(4 genes in 2 species)
specific family

Descriptions

gene_descr
DNA methyltransferase 3A

Identifiers

Type Value
UniprotO88508
MGI1261827

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0000278
IEA
Genome Projectmitotic cell cycle
GO:0006306
IDA, IGI
ISS, ISO
IEA
Genome ProjectDNA methylation
GO:0006346
IDA, IGI
Genome Projectmethylation-dependent chromatin silencing
GO:0006349
IDA, IMP
Genome Projectregulation of gene expression by genetic imprinting
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0007283
IMP
Genome Projectspermatogenesis
GO:0007568
IEA
Genome Projectaging
GO:0009636
IEA
Genome Projectresponse to toxic substance
GO:0010212
IEA
Genome Projectresponse to ionizing radiation
GO:0010216
TAS
Genome Projectmaintenance of DNA methylation
GO:0010288
IEA
Genome Projectresponse to lead ion
GO:0010424
IEA
Genome ProjectDNA methylation on cytosine within a CG sequence
GO:0010468
IEA
Genome Projectregulation of gene expression
GO:0010942
IEA
Genome Projectpositive regulation of cell death
GO:0016568
IEA
Genome Projectchromatin modification
GO:0030182
IEA
Genome Projectneuron differentiation
GO:0031667
IEA
Genome Projectresponse to nutrient levels
GO:0032259
IEA
Genome Projectmethylation
GO:0032355
IEA
Genome Projectresponse to estradiol
GO:0032776
IEA
Genome ProjectDNA methylation on cytosine
GO:0033189
IEA
Genome Projectresponse to vitamin A
GO:0036276
IEA
Genome Projectresponse to antidepressant
GO:0042220
IEA
Genome Projectresponse to cocaine
GO:0042493
IEA
Genome Projectresponse to drug
GO:0043045
IMP
Genome ProjectDNA methylation involved in embryo development
GO:0043046
IMP
Genome ProjectDNA methylation involved in gamete generation
GO:0044027
IDA
Genome Projecthypermethylation of CpG island
GO:0045471
IEA
Genome Projectresponse to ethanol
GO:0046498
IEA
Genome ProjectS-adenosylhomocysteine metabolic process
GO:0046499
IEA
Genome ProjectS-adenosylmethioninamine metabolic process
GO:0071230
IDA
Genome Projectcellular response to amino acid stimulus
GO:0071361
IEA
Genome Projectcellular response to ethanol
GO:0071456
IEA
Genome Projectcellular response to hypoxia
GO:0090116
ISO
Genome ProjectC-5 methylation of cytosine
GO:0097284
IEA
Genome Projecthepatocyte apoptotic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003677
IDA
ISS, ISO
IEA
Genome ProjectDNA binding
GO:0003682
IDA
IEA
Genome Projectchromatin binding
GO:0003886
IDA, IGI
ISS, ISO
IEA
Genome ProjectDNA (cytosine-5-)-methyltransferase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008168
TAS, IEA
Genome Projectmethyltransferase activity
GO:0009008
IEA
Genome ProjectDNA-methyltransferase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0042802
ISO
IEA
Genome Projectidentical protein binding
GO:0045322
IEA
Genome Projectunmethylated CpG binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0051718
IEA
Genome ProjectDNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates
GO:0051719
TAS
Genome ProjectDNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000775
IDA
Genome Projectchromosome, centromeric region
GO:0000791
ISS, ISO
IEA
Genome Projecteuchromatin
GO:0000792
IDA
Genome Projectheterochromatin
GO:0001741
IDA
Genome ProjectXY body
GO:0005634
IDA
ISS, ISO
IEA
Genome Projectnucleus
GO:0005654
ISO
TAS, IEA
Genome Projectnucleoplasm
GO:0005720
IDA
Genome Projectnuclear heterochromatin
GO:0005737
IDA
ISS, ISO
IEA
Genome Projectcytoplasm
GO:0016363
ISS, ISO
IEA
Genome Projectnuclear matrix

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000313PWWP domain
IPR001525C-5 cytosine methyltransferase
IPR018117DNA methylase, C-5 cytosine-specific, active site
IPR025766ADD domain
IPR029063S-adenosyl-L-methionine-dependent methyltransferase
IPR030487DNA (cytosine-5)-methyltransferase 3A

No MapMan annotations defined for this gene.