Gene: ENSMUSG00000020380 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000020380
Transcript Identifier
ENSMUST00000020649
Gene Type
Coding gene
Location
11 : 53650469-53707055 : negative

Family Information

Homologous gene family
HOM03P001713
(46 genes in 38 species)
specific family
Orthologous gene family
ORTHO03P001054
(41 genes in 36 species)
specific family

Descriptions

gene_descr
RAD50 homolog (S. cerevisiae)

Identifiers

Type Value
UniprotQ5SV02
MGI109292

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000019
ISO
IEA
Genome Projectregulation of mitotic recombination
GO:0000723
IEA
Genome Projecttelomere maintenance
GO:0000737
IEA
Genome ProjectDNA catabolic process, endonucleolytic
GO:0006281
ISO
IEA
Genome ProjectDNA repair
GO:0006302
ISO
IEA
Genome Projectdouble-strand break repair
GO:0006310
ISO
IEA
Genome ProjectDNA recombination
GO:0006974
ISO
IEA
Genome Projectcellular response to DNA damage stimulus
GO:0007004
ISO
IEA
Genome Projecttelomere maintenance via telomerase
GO:0007346
IMP
Genome Projectregulation of mitotic cell cycle
GO:0031954
ISO
IEA
Genome Projectpositive regulation of protein autophosphorylation
GO:0032508
ISO
IEA
Genome ProjectDNA duplex unwinding
GO:0033674
ISO
IEA
Genome Projectpositive regulation of kinase activity
GO:0051276
IMP
Genome Projectchromosome organization
GO:0070192
IMP
Genome Projectchromosome organization involved in meiotic cell cycle
GO:0090305
ISO
IEA
Genome Projectnucleic acid phosphodiester bond hydrolysis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000014
ISO
IEA
Genome Projectsingle-stranded DNA endodeoxyribonuclease activity
GO:0003677
ISO
IEA
Genome ProjectDNA binding
GO:0004003
ISO
IEA
Genome ProjectATP-dependent DNA helicase activity
GO:0008408
ISO
IEA
Genome Project3'-5' exonuclease activity
GO:0016887
IEA
Genome ProjectATPase activity
GO:0030674
ISO
IEA
Genome Projectprotein binding, bridging

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000784
ISO
IEA
Genome Projectnuclear chromosome, telomeric region
GO:0005634
IDA
IEA
Genome Projectnucleus
GO:0005654
ISO
IEA
Genome Projectnucleoplasm
GO:0016020
ISO
IEA
Genome Projectmembrane
GO:0030870
ISO
IEA
Genome ProjectMre11 complex
GO:0035861
ISO
IEA
Genome Projectsite of double-strand break
GO:0045120
IDA
Genome Projectpronucleus

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR004584DNA repair protein Rad50, eukaryotes
IPR013134RAD50, zinc hook
IPR027417P-loop containing nucleoside triphosphate hydrolase

No MapMan annotations defined for this gene.