Gene: ENSMUSG00000020349 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000020349
Transcript Identifier
ENSMUST00000020608
Gene Type
Coding gene
Location
11 : 52099049-52121974 : positive

Family Information

Homologous gene family
HOM03P000043
(553 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P000246
(59 genes in 38 species)
specific family

Descriptions

gene_descr
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform

Identifiers

Type Value
UniprotP63330
MGI1321159

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001932
ISO
Genome Projectregulation of protein phosphorylation
GO:0006470
TAS
Genome Projectprotein dephosphorylation
GO:0007498
IMP
Genome Projectmesoderm development
GO:0010469
ISO
Genome Projectregulation of receptor activity
GO:0010719
ISO
IEA
Genome Projectnegative regulation of epithelial to mesenchymal transition
GO:0031952
ISO
Genome Projectregulation of protein autophosphorylation
GO:0042176
ISO
Genome Projectregulation of protein catabolic process
GO:0051321
IEA
Genome Projectmeiotic cell cycle
GO:0051726
TAS
Genome Projectregulation of cell cycle
GO:0070208
ISO
Genome Projectprotein heterotrimerization
GO:0071902
ISO
IEA
Genome Projectpositive regulation of protein serine/threonine kinase activity

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004721
IEA
Genome Projectphosphoprotein phosphatase activity
GO:0004722
TAS
Genome Projectprotein serine/threonine phosphatase activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008022
IPI
Genome Projectprotein C-terminus binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0046982
ISS
Genome Projectprotein heterodimerization activity
GO:0046983
ISO
Genome Projectprotein dimerization activity
GO:0050811
IDA
Genome ProjectGABA receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000159
IDA
ISO
Genome Projectprotein phosphatase type 2A complex
GO:0000775
IDA
IEA
Genome Projectchromosome, centromeric region
GO:0000922
IEA
Genome Projectspindle pole
GO:0005634
IEA
Genome Projectnucleus
GO:0005694
IEA
Genome Projectchromosome
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005829
IDA
Genome Projectcytosol
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005886
IDA
Genome Projectplasma membrane
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR004843Calcineurin-like phosphoesterase domain, apaH type
IPR006186Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase
IPR029052Metallo-dependent phosphatase-like

No MapMan annotations defined for this gene.