Gene: ENSMUSG00000020275 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000020275
Transcript Identifier
ENSMUST00000102864
Gene Type
Coding gene
Location
11 : 23742265-23770689 : negative

Family Information

Homologous gene family
HOM03P008110
(10 genes in 3 species)
specific family
Orthologous gene family
ORTHO03P025181
(4 genes in 3 species)
specific family

Descriptions

gene_descr
reticuloendotheliosis oncogene

Identifiers

Type Value
UniprotA4QPD3
MGI97897

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IBA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001816
IMP
Genome Projectcytokine production
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006366
ISO
Genome Projecttranscription from RNA polymerase II promoter
GO:0006954
IBA
Genome Projectinflammatory response
GO:0007249
IBA
IEA
Genome ProjectI-kappaB kinase/NF-kappaB signaling
GO:0010629
ISO
IEA
Genome Projectnegative regulation of gene expression
GO:0032688
ISO
IEA
Genome Projectnegative regulation of interferon-beta production
GO:0034097
IBA
Genome Projectresponse to cytokine
GO:0038061
IBA
Genome ProjectNIK/NF-kappaB signaling
GO:0043123
IEA
Genome Projectpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045084
IMP
Genome Projectpositive regulation of interleukin-12 biosynthetic process
GO:0045087
IBA
Genome Projectinnate immune response
GO:0045893
IDA
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
ISO, IBA
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:1901215
IEA
Genome Projectnegative regulation of neuron death

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000977
IBA
Genome ProjectRNA polymerase II regulatory region sequence-specific DNA binding
GO:0000980
ISO
IEA
Genome ProjectRNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981
IBA
Genome ProjectRNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0001205
ISO
IEA
Genome Projecttranscriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0003682
IBA
Genome Projectchromatin binding
GO:0003700
IDA
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0043565
IEA
Genome Projectsequence-specific DNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
IC, IEA
Genome Projectnucleus
GO:0005654
IBA
Genome Projectnucleoplasm
GO:0005667
IEA
Genome Projecttranscription factor complex
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005829
IBA
Genome Projectcytosol
GO:0033256
IBA
Genome ProjectI-kappaB/NF-kappaB complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000451NF-kappa-B/Dorsal
IPR002909IPT domain
IPR008967p53-like transcription factor, DNA-binding
IPR011539Rel homology domain (RHD), DNA-binding domain
IPR013783Immunoglobulin-like fold
IPR014756Immunoglobulin E-set
IPR030492Rel homology domain, conserved site
IPR030505Proto-oncogene c-Rel
IPR032397Rel homology dimerisation domain

No MapMan annotations defined for this gene.