Gene: ENSMUSG00000020170 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000020170
Transcript Identifier
ENSMUST00000020381
Gene Type
Coding gene
Location
10 : 117073929-117081087 : negative

Family Information

Homologous gene family
HOM03P014966
(5 genes in 4 species)
specific family

Descriptions

gene_descr
fibroblast growth factor receptor substrate 2

Identifiers

Type Value
UniprotQ8C180
MGI1100860

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000187
IMP
Genome Projectactivation of MAPK activity
GO:0001702
IMP
Genome Projectgastrulation with mouth forming second
GO:0001759
IMP
Genome Projectorgan induction
GO:0002088
IMP
Genome Projectlens development in camera-type eye
GO:0003281
IMP
Genome Projectventricular septum development
GO:0007169
IDA
Genome Projecttransmembrane receptor protein tyrosine kinase signaling pathway
GO:0007405
IMP, IGI
Genome Projectneuroblast proliferation
GO:0008543
IMP, IGI
ISO
IEA
Genome Projectfibroblast growth factor receptor signaling pathway
GO:0008595
IMP
Genome Projectanterior/posterior axis specification, embryo
GO:0030900
IMP
Genome Projectforebrain development
GO:0042981
IMP
Genome Projectregulation of apoptotic process
GO:0046619
IMP
Genome Projectoptic placode formation involved in camera-type eye formation
GO:0050678
IMP
Genome Projectregulation of epithelial cell proliferation
GO:0060527
IMP
Genome Projectprostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0070307
IMP, IGI
Genome Projectlens fiber cell development
GO:0070372
IMP
Genome Projectregulation of ERK1 and ERK2 cascade

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005068
IDA
Genome Projecttransmembrane receptor protein tyrosine kinase adaptor activity
GO:0005104
ISO
IEA
Genome Projectfibroblast growth factor receptor binding
GO:0005158
IEA
Genome Projectinsulin receptor binding
GO:0005168
ISO
IEA
Genome Projectneurotrophin TRKA receptor binding
GO:0005515
IPI
Genome Projectprotein binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005886
IDA
Genome Projectplasma membrane
GO:0005911
IDA
Genome Projectcell-cell junction
GO:0016020
IEA
Genome Projectmembrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR002404IRS-type PTB domain
IPR011993PH domain-like

No MapMan annotations defined for this gene.