Gene: ENSMUSG00000020120 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000020120
Transcript Identifier
ENSMUST00000102881
Gene Type
Coding gene
Location
11 : 16974150-17008598 : negative

Family Information

Homologous gene family
HOM03P012787
(6 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P063352
(2 genes in 2 species)
specific family

Descriptions

gene_descr
pleckstrin

Identifiers

Type Value
UniprotQ9JHK5
UniprotQ5F271
MGI1860485

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002244
IEA
Genome Projecthematopoietic progenitor cell differentiation
GO:0002576
IEA
Genome Projectplatelet degranulation
GO:0007229
ISO
IEA
Genome Projectintegrin-mediated signaling pathway
GO:0010920
ISO
IEA
Genome Projectnegative regulation of inositol phosphate biosynthetic process
GO:0010925
ISO
IEA
Genome Projectpositive regulation of inositol-polyphosphate 5-phosphatase activity
GO:0030030
ISO
IEA
Genome Projectcell projection organization
GO:0030836
IMP
ISO
IEA
Genome Projectpositive regulation of actin filament depolymerization
GO:0030845
ISO
IEA
Genome Projectphospholipase C-inhibiting G-protein coupled receptor signaling pathway
GO:0030866
ISO
IEA
Genome Projectcortical actin cytoskeleton organization
GO:0031529
ISO
IEA
Genome Projectruffle organization
GO:0031532
ISO
IEA
Genome Projectactin cytoskeleton reorganization
GO:0032233
ISO
IEA
Genome Projectpositive regulation of actin filament bundle assembly
GO:0035556
IEA
Genome Projectintracellular signal transduction
GO:0045744
ISO
IEA
Genome Projectnegative regulation of G-protein coupled receptor protein signaling pathway
GO:0046488
ISO
IEA
Genome Projectphosphatidylinositol metabolic process
GO:0060305
ISO
IEA
Genome Projectregulation of cell diameter
GO:0070493
IMP
ISO
IEA
Genome Projectthrombin receptor signaling pathway
GO:0070527
IMP
ISO
Genome Projectplatelet aggregation
GO:0006904
IMP
Genome Projectvesicle docking involved in exocytosis
GO:0010572
IMP
Genome Projectpositive regulation of platelet activation
GO:0033625
IMP
Genome Projectpositive regulation of integrin activation
GO:0070528
IMP
Genome Projectprotein kinase C signaling
GO:0070560
IMP
Genome Projectprotein secretion by platelet

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005080
ISO
IEA
Genome Projectprotein kinase C binding
GO:0042803
ISO
IEA
Genome Projectprotein homodimerization activity
GO:0043325
ISO
IEA
Genome Projectphosphatidylinositol-3,4-bisphosphate binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0016020
ISO
IEA
Genome Projectmembrane
GO:0032587
ISO
IEA
Genome Projectruffle membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000591DEP domain
IPR001849Pleckstrin homology domain
IPR011991Winged helix-turn-helix DNA-binding domain
IPR011993PH domain-like

No MapMan annotations defined for this gene.