Gene: ENSMUSG00000020052 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000020052
Transcript Identifier
ENSMUST00000020243
Gene Type
Coding gene
Location
10 : 87492393-87493088 : negative

Family Information

Homologous gene family
HOM03P005004
(18 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P076574
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
achaete-scute complex homolog 1 (Drosophila)

Identifiers

Type Value
UniprotQ02067
MGI96919

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
ISO
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001764
IMP, IGI
Genome Projectneuron migration
GO:0003358
IMP
Genome Projectnoradrenergic neuron development
GO:0003359
ISO
IEA
Genome Projectnoradrenergic neuron fate commitment
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IDA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0007219
IGI
ISO
IEA
Genome ProjectNotch signaling pathway
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007346
IMP
Genome Projectregulation of mitotic cell cycle
GO:0007389
IMP
Genome Projectpattern specification process
GO:0007399
IEA
Genome Projectnervous system development
GO:0007400
IMP
Genome Projectneuroblast fate determination
GO:0007405
IGI
Genome Projectneuroblast proliferation
GO:0008593
IMP
Genome Projectregulation of Notch signaling pathway
GO:0010001
IGI
Genome Projectglial cell differentiation
GO:0010226
IEA
Genome Projectresponse to lithium ion
GO:0010468
IMP
Genome Projectregulation of gene expression
GO:0014003
IMP
Genome Projectoligodendrocyte development
GO:0021527
IMP
Genome Projectspinal cord association neuron differentiation
GO:0021529
IGI
Genome Projectspinal cord oligodendrocyte cell differentiation
GO:0021530
IMP
Genome Projectspinal cord oligodendrocyte cell fate specification
GO:0021750
IMP
Genome Projectvestibular nucleus development
GO:0021779
IMP
Genome Projectoligodendrocyte cell fate commitment
GO:0021879
IEA
Genome Projectforebrain neuron differentiation
GO:0021892
IEA
Genome Projectcerebral cortex GABAergic interneuron differentiation
GO:0021902
IMP
Genome Projectcommitment of neuronal cell to specific neuron type in forebrain
GO:0021954
IMP, IGI
Genome Projectcentral nervous system neuron development
GO:0021987
IMP
Genome Projectcerebral cortex development
GO:0022008
IDA
ISO
IEA
Genome Projectneurogenesis
GO:0030154
IMP
IEA
Genome Projectcell differentiation
GO:0030182
IMP, IGI
Genome Projectneuron differentiation
GO:0030856
IMP
Genome Projectregulation of epithelial cell differentiation
GO:0032526
IEA
Genome Projectresponse to retinoic acid
GO:0042127
IDA
Genome Projectregulation of cell proliferation
GO:0043066
ISO
IEA
Genome Projectnegative regulation of apoptotic process
GO:0043525
IMP
Genome Projectpositive regulation of neuron apoptotic process
GO:0045665
ISO
IEA
Genome Projectnegative regulation of neuron differentiation
GO:0045666
IDA
IEA
Genome Projectpositive regulation of neuron differentiation
GO:0045747
IMP
Genome Projectpositive regulation of Notch signaling pathway
GO:0045787
IDA
Genome Projectpositive regulation of cell cycle
GO:0045892
ISO
IEA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045944
IDA, IGI
ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048469
IMP
Genome Projectcell maturation
GO:0048484
TAS
Genome Projectenteric nervous system development
GO:0048485
TAS
Genome Projectsympathetic nervous system development
GO:0048486
TAS
Genome Projectparasympathetic nervous system development
GO:0048663
IMP, IGI
Genome Projectneuron fate commitment
GO:0048665
IMP
Genome Projectneuron fate specification
GO:0048666
IMP
Genome Projectneuron development
GO:0048699
IMP
Genome Projectgeneration of neurons
GO:0048709
IMP
Genome Projectoligodendrocyte differentiation
GO:0050767
IMP
Genome Projectregulation of neurogenesis
GO:0050769
IMP
Genome Projectpositive regulation of neurogenesis
GO:0050883
IMP
Genome Projectmusculoskeletal movement, spinal reflex action
GO:0051593
IEA
Genome Projectresponse to folic acid
GO:0060163
IMP
Genome Projectsubpallium neuron fate commitment
GO:0060165
IMP
Genome Projectregulation of timing of subpallium neuron differentiation
GO:0060166
IMP
Genome Projectolfactory pit development
GO:0060579
IMP
Genome Projectventral spinal cord interneuron fate commitment
GO:0061100
IMP
Genome Projectlung neuroendocrine cell differentiation
GO:0061102
IMP
Genome Projectstomach neuroendocrine cell differentiation
GO:0061103
IMP
Genome Projectcarotid body glomus cell differentiation
GO:0061104
IMP
Genome Projectadrenal chromaffin cell differentiation
GO:0061549
IMP
Genome Projectsympathetic ganglion development
GO:0070849
IEA
Genome Projectresponse to epidermal growth factor
GO:0071259
IEA
Genome Projectcellular response to magnetism
GO:2000179
IMP
Genome Projectpositive regulation of neural precursor cell proliferation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000978
ISO
IEA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000989
IDA
Genome Projecttranscription factor activity, transcription factor binding
GO:0001078
ISO
IEA
Genome Projecttranscriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0003677
IDA
IEA
Genome ProjectDNA binding
GO:0003682
IDA
Genome Projectchromatin binding
GO:0003690
IEA
Genome Projectdouble-stranded DNA binding
GO:0003700
IDA
ISO
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0042803
IEA
Genome Projectprotein homodimerization activity
GO:0043425
ISO
IEA
Genome ProjectbHLH transcription factor binding
GO:0043565
IDA
Genome Projectsequence-specific DNA binding
GO:0046983
IEA
Genome Projectprotein dimerization activity
GO:0070888
ISO
IEA
Genome ProjectE-box binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0043025
IDA
Genome Projectneuronal cell body

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
IPR015660Achaete-scute transcription factor-related

No MapMan annotations defined for this gene.