Gene: ENSMUSG00000019979 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000019979
Transcript Identifier
ENSMUST00000020157
Gene Type
Coding gene
Location
10 : 90991450-91080024 : negative

Family Information

Homologous gene family
HOM03P000003
(2229 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P001140
(40 genes in 39 species)
specific family

Descriptions

gene_descr
apoptotic peptidase activating factor 1

Identifiers

Type Value
UniprotO88879
MGI1306796

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001666
IEA
Genome Projectresponse to hypoxia
GO:0001843
IMP
Genome Projectneural tube closure
GO:0006915
IEA
Genome Projectapoptotic process
GO:0006919
IMP, IGI
ISO
IEA
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007275
IMP
Genome Projectmulticellular organismal development
GO:0007420
IMP
IEA
Genome Projectbrain development
GO:0007568
IEA
Genome Projectaging
GO:0007584
IEA
Genome Projectresponse to nutrient
GO:0008635
ISO, IBA
IEA
Genome Projectactivation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
GO:0010659
IEA
Genome Projectcardiac muscle cell apoptotic process
GO:0030154
IEA
Genome Projectcell differentiation
GO:0030900
IMP
Genome Projectforebrain development
GO:0034349
IEA
Genome Projectglial cell apoptotic process
GO:0042981
IEA
Genome Projectregulation of apoptotic process
GO:0051260
IEA
Genome Projectprotein homooligomerization
GO:0051402
IGI
Genome Projectneuron apoptotic process
GO:0070059
IMP
Genome Projectintrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0071560
IEA
Genome Projectcellular response to transforming growth factor beta stimulus
GO:0097190
IEA
Genome Projectapoptotic signaling pathway
GO:1902510
IGI
Genome Projectregulation of apoptotic DNA fragmentation
GO:2001235
IGI
Genome Projectpositive regulation of apoptotic signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0005524
IEA
Genome ProjectATP binding
GO:0008656
IPI
Genome Projectcysteine-type endopeptidase activator activity involved in apoptotic process
GO:0031072
IEA
Genome Projectheat shock protein binding
GO:0042802
IPI
IEA
Genome Projectidentical protein binding
GO:0043531
IEA
Genome ProjectADP binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
Genome Projectnucleus
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005829
IDA
TAS
Genome Projectcytosol
GO:0043293
ISO, IBA
IEA
Genome Projectapoptosome
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001315CARD domain
IPR001680WD40 repeat
IPR002182NB-ARC
IPR011029Death-like domain
IPR015943WD40/YVTN repeat-like-containing domain
IPR017251Apoptotic protease-activating factor 1
IPR017986WD40-repeat-containing domain
IPR019775WD40 repeat, conserved site
IPR020472G-protein beta WD-40 repeat
IPR027417P-loop containing nucleoside triphosphate hydrolase

No MapMan annotations defined for this gene.