Gene: ENSMUSG00000019893 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000019893
Transcript Identifier
ENSMUST00000020045
Gene Type
Coding gene
Location
10 : 52046016-52194956 : negative

Family Information

Homologous gene family
HOM03P000004
(1817 genes in 37 species)
specific family
Orthologous gene family
ORTHO03P028591
(4 genes in 4 species)
specific family
Duplication type
Block duplicate

Descriptions

gene_descr
Ros1 proto-oncogene

Identifiers

Type Value
UniprotQ78DX7
MGI97999

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002066
IMP
Genome Projectcolumnar/cuboidal epithelial cell development
GO:0006468
IDA
ISO
IEA
Genome Projectprotein phosphorylation
GO:0007283
IMP
Genome Projectspermatogenesis
GO:0008283
IDA
Genome Projectcell proliferation
GO:0010629
IMP
Genome Projectnegative regulation of gene expression
GO:0010966
IMP
Genome Projectregulation of phosphate transport
GO:0016049
ISS, ISO
IEA
Genome Projectcell growth
GO:0016310
IEA
Genome Projectphosphorylation
GO:0023014
IDA
Genome Projectsignal transduction by protein phosphorylation
GO:0030154
IDA
Genome Projectcell differentiation
GO:0032006
ISS, ISO
IEA
Genome Projectregulation of TOR signaling
GO:0038083
IDA
Genome Projectpeptidyl-tyrosine autophosphorylation
GO:0070372
IDA
Genome Projectregulation of ERK1 and ERK2 cascade

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0004672
IEA
Genome Projectprotein kinase activity
GO:0004713
ISS, ISO
IEA
Genome Projectprotein tyrosine kinase activity
GO:0004714
IEA
Genome Projecttransmembrane receptor protein tyrosine kinase activity
GO:0005524
IEA
Genome ProjectATP binding
GO:0016301
IEA
Genome Projectkinase activity
GO:0016740
IEA
Genome Projecttransferase activity
GO:0019903
IPI
ISO
IEA
Genome Projectprotein phosphatase binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005886
IEA
Genome Projectplasma membrane
GO:0009986
IDA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0048471
IDA
Genome Projectperinuclear region of cytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000033LDLR class B repeat
IPR000719Protein kinase domain
IPR001245Serine-threonine/tyrosine-protein kinase catalytic domain
IPR003961Fibronectin type III
IPR008266Tyrosine-protein kinase, active site
IPR011009Protein kinase-like domain
IPR011042Six-bladed beta-propeller, TolB-like
IPR013783Immunoglobulin-like fold
IPR017441Protein kinase, ATP binding site
IPR020635Tyrosine-protein kinase, catalytic domain

No MapMan annotations defined for this gene.