Gene: ENSMUSG00000018924 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000018924
Transcript Identifier
ENSMUST00000019068
Gene Type
Coding gene
Location
11 : 70344543-70352005 : negative

Family Information

Homologous gene family
HOM03P000704
(78 genes in 15 species)
specific family
Orthologous gene family
ORTHO03P000181
(65 genes in 15 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
arachidonate 15-lipoxygenase

Identifiers

Type Value
UniprotP39654
UniprotA2CF88
MGI87997

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001503
IMP
Genome Projectossification
GO:0010811
ISS, ISO
IEA
Genome Projectpositive regulation of cell-substrate adhesion
GO:0019369
IDA, IMP
ISO
IEA
Genome Projectarachidonic acid metabolic process
GO:0019372
IDA, IMP
ISO
IEA
Genome Projectlipoxygenase pathway
GO:0030282
IMP
Genome Projectbone mineralization
GO:0034116
IEA
Genome Projectpositive regulation of heterotypic cell-cell adhesion
GO:0035963
ISS, ISO
IEA
Genome Projectcellular response to interleukin-13
GO:0051122
ISS
IEA
Genome Projecthepoxilin biosynthetic process
GO:0055114
IEA
Genome Projectoxidation-reduction process
GO:0070374
ISS, ISO
IEA
Genome Projectpositive regulation of ERK1 and ERK2 cascade
GO:0071277
ISS, ISO
IEA
Genome Projectcellular response to calcium ion
GO:0002820
IMP
Genome Projectnegative regulation of adaptive immune response
GO:0006629
IEA
Genome Projectlipid metabolic process
GO:0006631
IEA
Genome Projectfatty acid metabolic process
GO:0006646
IMP
Genome Projectphosphatidylethanolamine biosynthetic process
GO:0030838
IMP
Genome Projectpositive regulation of actin filament polymerization
GO:0034976
IMP
Genome Projectresponse to endoplasmic reticulum stress
GO:0035358
IMP
Genome Projectregulation of peroxisome proliferator activated receptor signaling pathway
GO:0042060
IMP
Genome Projectwound healing
GO:0043277
IMP
Genome Projectapoptotic cell clearance
GO:1901074
IMP
Genome Projectregulation of engulfment of apoptotic cell
GO:2001303
IMP
Genome Projectlipoxin A4 biosynthetic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004052
IDA
ISO
IEA
Genome Projectarachidonate 12-lipoxygenase activity
GO:0005506
ISS
IEA
Genome Projectiron ion binding
GO:0005546
ISS, ISO
IEA
Genome Projectphosphatidylinositol-4,5-bisphosphate binding
GO:0016491
IEA
Genome Projectoxidoreductase activity
GO:0016702
IEA
Genome Projectoxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0047977
IEA
Genome Projecthepoxilin-epoxide hydrolase activity
GO:0050473
IDA
ISO
IEA
Genome Projectarachidonate 15-lipoxygenase activity
GO:0051120
IEA
Genome Projecthepoxilin A3 synthase activity
GO:0051213
IEA
Genome Projectdioxygenase activity
GO:0008289
IEA
Genome Projectlipid binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
IEA
Genome Projectcytoplasm
GO:0005811
ISS, ISO
IEA
Genome Projectlipid particle
GO:0005829
IDA
ISO
IEA
Genome Projectcytosol
GO:0016020
ISS, ISO
IEA
Genome Projectmembrane
GO:0031234
ISS, ISO
IEA
Genome Projectextrinsic component of cytoplasmic side of plasma membrane
GO:0005886
IDA
IEA
Genome Projectplasma membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000907Lipoxygenase
IPR001024PLAT/LH2 domain
IPR001885Lipoxygenase, mammalian
IPR013819Lipoxygenase, C-terminal
IPR020833Lipoxygenase, iron binding site
IPR020834Lipoxygenase, conserved site

No MapMan annotations defined for this gene.