Gene: ENSMUSG00000018916 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000018916
Transcript Identifier
ENSMUST00000019060
Gene Type
Coding gene
Location
11 : 54247588-54249610 : negative

Family Information

Homologous gene family
HOM03P039086
(2 genes in 2 species)
specific family

Descriptions

gene_descr
colony stimulating factor 2 (granulocyte-macrophage)

Identifiers

Type Value
UniprotP01587
UniprotQ5SX78
MGI1339752

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001892
IMP
Genome Projectembryonic placenta development
GO:0006955
IEA
Genome Projectimmune response
GO:0008284
IDA
Genome Projectpositive regulation of cell proliferation
GO:0010468
IDA, IMP
Genome Projectregulation of gene expression
GO:0010628
ISO
IEA
Genome Projectpositive regulation of gene expression
GO:0010744
ISO
IEA
Genome Projectpositive regulation of macrophage derived foam cell differentiation
GO:0032747
ISO
IEA
Genome Projectpositive regulation of interleukin-23 production
GO:0042045
IEA
Genome Projectepithelial fluid transport
GO:0042116
IEA
Genome Projectmacrophage activation
GO:0042127
IGI
Genome Projectregulation of cell proliferation
GO:0042523
ISO
IEA
Genome Projectpositive regulation of tyrosine phosphorylation of Stat5 protein
GO:0043011
IDA
Genome Projectmyeloid dendritic cell differentiation
GO:0045740
ISO
IEA
Genome Projectpositive regulation of DNA replication
GO:0045918
ISO
IEA
Genome Projectnegative regulation of cytolysis
GO:0071222
IEA
Genome Projectcellular response to lipopolysaccharide
GO:0071803
ISO
IEA
Genome Projectpositive regulation of podosome assembly
GO:0097028
ISO
IEA
Genome Projectdendritic cell differentiation
GO:2001240
ISO
IEA
Genome Projectnegative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005125
IDA
IEA
Genome Projectcytokine activity
GO:0005129
IEA
Genome Projectgranulocyte macrophage colony-stimulating factor receptor binding
GO:0008083
IEA
Genome Projectgrowth factor activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005615
IDA
IEA
Genome Projectextracellular space

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000773Granulocyte-macrophage colony-stimulating factor
IPR009079Four-helical cytokine-like, core
IPR012351Four-helical cytokine, core

No MapMan annotations defined for this gene.