Gene: ENSMUSG00000018654 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000018654
Transcript Identifier
ENSMUST00000065433
Gene Type
Coding gene
Location
11 : 11700219-11769581 : positive

Family Information

Homologous gene family
HOM03P000007
(1601 genes in 28 species)
specific family
Orthologous gene family
ORTHO03P076537
(2 genes in 2 species)
specific family

Descriptions

gene_descr
IKAROS family zinc finger 1

Identifiers

Type Value
UniprotQ5SWT9
MGI1342540

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001779
IMP
Genome Projectnatural killer cell differentiation
GO:0006355
IMP
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IMP
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0030097
IMP
Genome Projecthemopoiesis
GO:0030098
ISO
Genome Projectlymphocyte differentiation
GO:0030183
IMP
Genome ProjectB cell differentiation
GO:0030217
IMP
Genome ProjectT cell differentiation
GO:0030218
ISO
Genome Projecterythrocyte differentiation
GO:0030900
IMP
Genome Projectforebrain development
GO:0035881
IDA
Genome Projectamacrine cell differentiation
GO:0040018
IMP, IGI
Genome Projectpositive regulation of multicellular organism growth
GO:0045579
IMP
Genome Projectpositive regulation of B cell differentiation
GO:0045660
IMP
Genome Projectpositive regulation of neutrophil differentiation
GO:0045892
IDA
Genome Projectnegative regulation of transcription, DNA-templated
GO:0045893
IDA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048535
IMP
Genome Projectlymph node development
GO:0048538
IMP
Genome Projectthymus development
GO:0048541
IMP
Genome ProjectPeyer's patch development
GO:0048732
IMP
Genome Projectgland development
GO:0051138
IMP
Genome Projectpositive regulation of NK T cell differentiation
GO:0060040
IDA
Genome Projectretinal bipolar neuron differentiation
GO:0060041
IMP
Genome Projectretina development in camera-type eye

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003676
IEA
Genome Projectnucleic acid binding
GO:0003677
IDA
ISO
Genome ProjectDNA binding
GO:0003700
IDA, IMP
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0043565
IMP
Genome Projectsequence-specific DNA binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0046982
IPI
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
Genome Projectnucleus
GO:0005667
TAS
Genome Projecttranscription factor complex
GO:0005721
IDA
Genome Projectpericentric heterochromatin
GO:0043234
ISO
Genome Projectprotein complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR007087Zinc finger, C2H2
IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
IPR015880Zinc finger, C2H2-like

No MapMan annotations defined for this gene.