Gene: ENSMUSG00000018501 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000018501
Transcript Identifier
ENSMUST00000101066
Gene Type
Coding gene
Location
11 : 62317843-62438445 : negative

Family Information

Homologous gene family
HOM03P008869
(9 genes in 7 species)
specific family
Orthologous gene family
ORTHO03P069609
(2 genes in 2 species)
specific family

Descriptions

gene_descr
nuclear receptor co-repressor 1

Identifiers

Type Value
UniprotQ5RIM6
MGI1349717

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IMP, IGI
ISO
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0002155
IGI
Genome Projectregulation of thyroid hormone mediated signaling pathway
GO:0002361
IMP
Genome ProjectCD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO:0006357
IGI
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0014067
IMP
Genome Projectnegative regulation of phosphatidylinositol 3-kinase signaling
GO:0021794
IMP
Genome Projectthalamus development
GO:0031065
IDA
Genome Projectpositive regulation of histone deacetylation
GO:0032922
IGI
Genome Projectcircadian regulation of gene expression
GO:0040014
IGI
Genome Projectregulation of multicellular organism growth
GO:0042632
IMP
Genome Projectcholesterol homeostasis
GO:0045892
IDA, IMP
Genome Projectnegative regulation of transcription, DNA-templated
GO:0046329
ISO
IEA
Genome Projectnegative regulation of JNK cascade
GO:0051225
ISO
IEA
Genome Projectspindle assembly
GO:0060318
IMP
Genome Projectdefinitive erythrocyte differentiation
GO:0072362
ISO
IEA
Genome Projectregulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter
GO:0072368
ISO
IEA
Genome Projectregulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter
GO:1904017
IGI
Genome Projectcellular response to Thyroglobulin triiodothyronine

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001102
ISO
IEA
Genome ProjectRNA polymerase II activating transcription factor binding
GO:0003677
IDA
IEA
Genome ProjectDNA binding
GO:0003700
IDA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003714
IGI
ISO
IEA
Genome Projecttranscription corepressor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0016922
IBA
Genome Projectligand-dependent nuclear receptor binding
GO:0035033
IDA, IMP
Genome Projecthistone deacetylase regulator activity
GO:0035257
ISO
IEA
Genome Projectnuclear hormone receptor binding
GO:0042826
ISO
IEA
Genome Projecthistone deacetylase binding
GO:0042974
IDA
Genome Projectretinoic acid receptor binding
GO:0043565
IDA
Genome Projectsequence-specific DNA binding
GO:0046965
IDA
Genome Projectretinoid X receptor binding
GO:0046966
IDA, IPI
Genome Projectthyroid hormone receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000118
ISO
IEA
Genome Projecthistone deacetylase complex
GO:0000790
ISO
IEA
Genome Projectnuclear chromatin
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005667
IPI
Genome Projecttranscription factor complex
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005876
ISO
IEA
Genome Projectspindle microtubule
GO:0016020
ISO
IEA
Genome Projectmembrane
GO:0016580
ISO, IBA
IEA
Genome ProjectSin3 complex
GO:0017053
IPI
ISO
IEA
Genome Projecttranscriptional repressor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR001005SANT/Myb domain
IPR009057Homeodomain-like
IPR017884SANT domain
IPR031557N-CoR, GPS2-interacting domain

No MapMan annotations defined for this gene.