Gene: ENSMUSG00000018363 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000018363
Transcript Identifier
ENSMUST00000167787
Gene Type
Coding gene
Location
11 : 106822665-106920232 : negative

Family Information

Homologous gene family
HOM03P000060
(418 genes in 39 species)
specific family
Orthologous gene family
ORTHO03P003574
(23 genes in 8 species)
specific family

Descriptions

gene_descr
SMAD specific E3 ubiquitin protein ligase 2

Identifiers

Type Value
UniprotA2A5Z6
MGI1913563

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006511
ISO
IEA
Genome Projectubiquitin-dependent protein catabolic process
GO:0007179
IBA
Genome Projecttransforming growth factor beta receptor signaling pathway
GO:0016567
IEA
Genome Projectprotein ubiquitination
GO:0030512
ISO
IEA
Genome Projectnegative regulation of transforming growth factor beta receptor signaling pathway
GO:0030579
ISO
IEA
Genome Projectubiquitin-dependent SMAD protein catabolic process
GO:0042787
IBA
Genome Projectprotein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:1901165
ISO
IEA
Genome Projectpositive regulation of trophoblast cell migration

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004842
ISO, IBA
IEA
Genome Projectubiquitin-protein transferase activity
GO:0005160
IEA
Genome Projecttransforming growth factor beta receptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0016874
IEA
Genome Projectligase activity
GO:0042802
ISO
IEA
Genome Projectidentical protein binding
GO:0046332
ISO
IEA
Genome ProjectSMAD binding
GO:0061630
TAS
Genome Projectubiquitin protein ligase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000151
ISO
IEA
Genome Projectubiquitin ligase complex
GO:0005634
IEA
Genome Projectnucleus
GO:0005737
IBA
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0005886
IEA
Genome Projectplasma membrane
GO:0016020
IEA
Genome Projectmembrane
GO:0045121
IEA
Genome Projectmembrane raft

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000008C2 domain
IPR000569HECT domain
IPR001202WW domain

No MapMan annotations defined for this gene.