Gene: ENSMUSG00000018293 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000018293
Transcript Identifier
ENSMUST00000018437
Gene Type
Coding gene
Location
11 : 70652124-70654480 : negative

Family Information

Homologous gene family
HOM03P014216
(6 genes in 2 species)
specific family
Orthologous gene family
ORTHO03P000907
(42 genes in 28 species)
specific family

Descriptions

gene_descr
profilin 1

Identifiers

Type Value
UniprotP62962
UniprotQ5SX50
MGI97549

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001843
IGI
Genome Projectneural tube closure
GO:0006357
IGI
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0008064
TAS, IEA
Genome Projectregulation of actin polymerization or depolymerization
GO:0010033
IEA
Genome Projectresponse to organic substance
GO:0010634
ISO
IEA
Genome Projectpositive regulation of epithelial cell migration
GO:0030036
IEA
Genome Projectactin cytoskeleton organization
GO:0030837
ISO
IEA
Genome Projectnegative regulation of actin filament polymerization
GO:0030838
ISO
IEA
Genome Projectpositive regulation of actin filament polymerization
GO:0032232
ISO
IEA
Genome Projectnegative regulation of actin filament bundle assembly
GO:0032781
ISO
IEA
Genome Projectpositive regulation of ATPase activity
GO:0042989
TAS
Genome Projectsequestering of actin monomers
GO:0045944
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0050434
IEA
Genome Projectpositive regulation of viral transcription
GO:0050821
ISO
Genome Projectprotein stabilization
GO:0051054
IEA
Genome Projectpositive regulation of DNA metabolic process
GO:0051496
IEA
Genome Projectpositive regulation of stress fiber assembly
GO:0051497
ISO
IEA
Genome Projectnegative regulation of stress fiber assembly
GO:0071363
IEA
Genome Projectcellular response to growth factor stimulus
GO:1900029
ISO
IEA
Genome Projectpositive regulation of ruffle assembly

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000774
ISO
IEA
Genome Projectadenyl-nucleotide exchange factor activity
GO:0003779
ISO
IEA
Genome Projectactin binding
GO:0003785
ISO
Genome Projectactin monomer binding
GO:0005102
IEA
Genome Projectreceptor binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0005546
ISO
IEA
Genome Projectphosphatidylinositol-4,5-bisphosphate binding
GO:0017048
IPI
Genome ProjectRho GTPase binding
GO:0044822
ISO
IEA
Genome Projectpoly(A) RNA binding
GO:0070064
ISO
IEA
Genome Projectproline-rich region binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
TAS
Genome Projectextracellular region
GO:0005634
IDA
ISO
Genome Projectnucleus
GO:0005737
IDA
ISO
IEA
Genome Projectcytoplasm
GO:0005829
TAS
Genome Projectcytosol
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005925
ISO
IEA
Genome Projectfocal adhesion
GO:0005938
ISO
Genome Projectcell cortex
GO:0016020
ISO
IEA
Genome Projectmembrane
GO:0043005
IEA
Genome Projectneuron projection
GO:0045202
IEA
Genome Projectsynapse
GO:0070062
ISO
IEA
Genome Projectextracellular exosome
GO:0072562
ISO
IEA
Genome Projectblood microparticle

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR005454Profilin1/2/3, vertebrate
IPR005455Profilin
IPR027310Profilin conserved site

No MapMan annotations defined for this gene.