Gene: ENSMUSG00000018160 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000018160
Transcript Identifier
ENSMUST00000107545
Gene Type
Coding gene
Location
11 : 98155241-98193083 : negative

Family Information

Homologous gene family
HOM03P041213
(2 genes in 2 species)
specific family

Descriptions

gene_descr
mediator complex subunit 1

Identifiers

Type Value
UniprotQ925J9
MGI1100846

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IMP
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0000902
ISS, ISO
IEA
Genome Projectcell morphogenesis
GO:0001525
IMP
Genome Projectangiogenesis
GO:0001701
IMP
Genome Projectin utero embryonic development
GO:0001889
IMP
Genome Projectliver development
GO:0001892
IMP
Genome Projectembryonic placenta development
GO:0002088
IMP
Genome Projectlens development in camera-type eye
GO:0002154
ISS, ISO
IEA
Genome Projectthyroid hormone mediated signaling pathway
GO:0003222
IMP
Genome Projectventricular trabecula myocardium morphogenesis
GO:0003406
IMP
Genome Projectretinal pigment epithelium development
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IDA, IMP
TAS, IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006356
ISS, ISO
IEA
Genome Projectregulation of transcription from RNA polymerase I promoter
GO:0006357
IEA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0006366
IC
Genome Projecttranscription from RNA polymerase II promoter
GO:0006367
ISS, ISO
IEA
Genome Projecttranscription initiation from RNA polymerase II promoter
GO:0006590
IMP
Genome Projectthyroid hormone generation
GO:0006702
ISS, ISO
IEA
Genome Projectandrogen biosynthetic process
GO:0007275
IMP
IEA
Genome Projectmulticellular organismal development
GO:0007420
IMP
IEA
Genome Projectbrain development
GO:0007507
IMP
Genome Projectheart development
GO:0007595
IMP
Genome Projectlactation
GO:0008284
IMP
Genome Projectpositive regulation of cell proliferation
GO:0009887
IMP
Genome Projectorgan morphogenesis
GO:0010628
ISS, ISO
IEA
Genome Projectpositive regulation of gene expression
GO:0010839
ISS, ISO
IEA
Genome Projectnegative regulation of keratinocyte proliferation
GO:0016567
IEA
Genome Projectprotein ubiquitination
GO:0030216
ISS, ISO
IEA
Genome Projectkeratinocyte differentiation
GO:0030224
IMP
Genome Projectmonocyte differentiation
GO:0030518
ISS, ISO
IEA
Genome Projectintracellular steroid hormone receptor signaling pathway
GO:0030521
ISS, ISO
IEA
Genome Projectandrogen receptor signaling pathway
GO:0031100
IMP
Genome Projectorgan regeneration
GO:0033148
IMP
Genome Projectpositive regulation of intracellular estrogen receptor signaling pathway
GO:0033160
IMP
Genome Projectpositive regulation of protein import into nucleus, translocation
GO:0033598
IMP
Genome Projectmammary gland epithelial cell proliferation
GO:0033601
IMP
Genome Projectpositive regulation of mammary gland epithelial cell proliferation
GO:0035050
IMP
Genome Projectembryonic heart tube development
GO:0035116
IMP
Genome Projectembryonic hindlimb morphogenesis
GO:0035162
IMP
Genome Projectembryonic hemopoiesis
GO:0035357
IMP
Genome Projectperoxisome proliferator activated receptor signaling pathway
GO:0035729
IMP
Genome Projectcellular response to hepatocyte growth factor stimulus
GO:0035855
IMP
Genome Projectmegakaryocyte development
GO:0042789
IMP
Genome ProjectmRNA transcription from RNA polymerase II promoter
GO:0043010
IMP
Genome Projectcamera-type eye development
GO:0043066
IMP
Genome Projectnegative regulation of apoptotic process
GO:0045444
IMP
ISO
IEA
Genome Projectfat cell differentiation
GO:0045618
ISS, ISO
IEA
Genome Projectpositive regulation of keratinocyte differentiation
GO:0045648
ISS, ISO
Genome Projectpositive regulation of erythrocyte differentiation
GO:0045665
IMP
Genome Projectnegative regulation of neuron differentiation
GO:0045893
ISO
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA, IMP
ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048821
IMP
Genome Projecterythrocyte development
GO:0048822
IMP
Genome Projectenucleate erythrocyte development
GO:0060335
IMP
Genome Projectpositive regulation of interferon-gamma-mediated signaling pathway
GO:0060744
IMP
Genome Projectmammary gland branching involved in thelarche
GO:0060745
IMP
Genome Projectmammary gland branching involved in pregnancy
GO:0060750
IMP
Genome Projectepithelial cell proliferation involved in mammary gland duct elongation
GO:0070318
IMP
Genome Projectpositive regulation of G0 to G1 transition
GO:0070371
ISO
IEA
Genome ProjectERK1 and ERK2 cascade
GO:0070562
IMP
Genome Projectregulation of vitamin D receptor signaling pathway
GO:0071364
ISS, ISO
IEA
Genome Projectcellular response to epidermal growth factor stimulus
GO:0071383
ISO
IEA
Genome Projectcellular response to steroid hormone stimulus
GO:0097067
ISO, IBA
IEA
Genome Projectcellular response to thyroid hormone stimulus
GO:2000273
ISO
IEA
Genome Projectpositive regulation of receptor activity
GO:2000347
IMP
Genome Projectpositive regulation of hepatocyte proliferation
GO:2001141
ISS, ISO
IEA
Genome Projectregulation of RNA biosynthetic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000978
IEA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981
IMP
Genome ProjectRNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0001047
IDA
ISS, ISO
IEA
Genome Projectcore promoter binding
GO:0001104
ISS, ISO, IBA
IEA
Genome ProjectRNA polymerase II transcription cofactor activity
GO:0003677
IDA
IEA
Genome ProjectDNA binding
GO:0003682
IDA
ISO
IEA
Genome Projectchromatin binding
GO:0003712
ISO
IEA
Genome Projecttranscription cofactor activity
GO:0003713
IDA
ISO
TAS, IEA
Genome Projecttranscription coactivator activity
GO:0004872
ISS, ISO
IEA
Genome Projectreceptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
IPI
ISO
IEA
Genome Projecttranscription factor binding
GO:0016922
ISO
IEA
Genome Projectligand-dependent nuclear receptor binding
GO:0030331
ISO
IEA
Genome Projectestrogen receptor binding
GO:0030374
ISS, ISO
Genome Projectligand-dependent nuclear receptor transcription coactivator activity
GO:0030375
ISO, IBA
IEA
Genome Projectthyroid hormone receptor coactivator activity
GO:0031490
IEA
Genome Projectchromatin DNA binding
GO:0032403
IDA
IEA
Genome Projectprotein complex binding
GO:0035257
IPI
ISO
IEA
Genome Projectnuclear hormone receptor binding
GO:0036033
ISO
IEA
Genome Projectmediator complex binding
GO:0042809
ISO, IBA
IEA
Genome Projectvitamin D receptor binding
GO:0042974
ISO, IBA
IEA
Genome Projectretinoic acid receptor binding
GO:0042975
ISO
IEA
Genome Projectperoxisome proliferator activated receptor binding
GO:0046966
ISS, ISO, IBA
IEA
Genome Projectthyroid hormone receptor binding
GO:0050693
ISO
IEA
Genome ProjectLBD domain binding
GO:0061630
IEA
Genome Projectubiquitin protein ligase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000151
IEA
Genome Projectubiquitin ligase complex
GO:0000785
IEA
Genome Projectchromatin
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005654
ISO
TAS, IEA
Genome Projectnucleoplasm
GO:0005730
ISS, ISO
IEA
Genome Projectnucleolus
GO:0016020
ISO
IEA
Genome Projectmembrane
GO:0016592
IDA
ISO
IEA
Genome Projectmediator complex
GO:0032993
IEA
Genome Projectprotein-DNA complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR019680Mediator complex, subunit Med1

No MapMan annotations defined for this gene.