Gene: ENSMUSG00000017969 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000017969
Transcript Identifier
ENSMUST00000088041
Gene Type
Coding gene
Location
2 : 167191817-167240420 : negative

Family Information

Homologous gene family
HOM03P007987
(10 genes in 3 species)
specific family
Orthologous gene family
ORTHO03P069058
(2 genes in 2 species)
specific family

Descriptions

gene_descr
prostaglandin I2 (prostacyclin) synthase

Identifiers

Type Value
UniprotQ8BXC0
MGI1097156

Toolbox

Explore

Create

View

Browse

 

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001516
ISO, IBA
IEA
Genome Projectprostaglandin biosynthetic process
GO:0006629
IEA
Genome Projectlipid metabolic process
GO:0006631
IEA
Genome Projectfatty acid metabolic process
GO:0006633
IEA
Genome Projectfatty acid biosynthetic process
GO:0006693
IEA
Genome Projectprostaglandin metabolic process
GO:0007566
IDA
Genome Projectembryo implantation
GO:0032088
ISO
Genome Projectnegative regulation of NF-kappaB transcription factor activity
GO:0035360
ISO
Genome Projectpositive regulation of peroxisome proliferator activated receptor signaling pathway
GO:0042981
IBA
Genome Projectregulation of apoptotic process
GO:0045019
ISO
Genome Projectnegative regulation of nitric oxide biosynthetic process
GO:0045766
ISO
Genome Projectpositive regulation of angiogenesis
GO:0046697
IDA
Genome Projectdecidualization
GO:0050728
ISO
Genome Projectnegative regulation of inflammatory response
GO:0055114
IEA
Genome Projectoxidation-reduction process
GO:0071456
ISO
Genome Projectcellular response to hypoxia
GO:0097190
ISO
Genome Projectapoptotic signaling pathway
GO:1900119
ISO
Genome Projectpositive regulation of execution phase of apoptosis

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004497
IEA
Genome Projectmonooxygenase activity
GO:0005506
IEA
Genome Projectiron ion binding
GO:0008116
ISO, IBA
IEA
Genome Projectprostaglandin-I synthase activity
GO:0016491
IEA
Genome Projectoxidoreductase activity
GO:0016705
IEA
Genome Projectoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037
ISO, IBA
IEA
Genome Projectheme binding
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
Genome Projectnucleus
GO:0005737
IDA
Genome Projectcytoplasm
GO:0005783
ISO, IBA
IEA
Genome Projectendoplasmic reticulum
GO:0005789
IEA
Genome Projectendoplasmic reticulum membrane
GO:0005901
ISO
Genome Projectcaveola
GO:0016020
IEA
Genome Projectmembrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001128Cytochrome P450
IPR002403Cytochrome P450, E-class, group IV
IPR024204Cytochrome P450, cholesterol 7-alpha-monooxygenase-type
IPR027286Prostacyclin synthase

No MapMan annotations defined for this gene.