Gene: ENSMUSG00000017830 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000017830
Transcript Identifier
ENSMUST00000017974
Gene Type
Coding gene
Location
11 : 100695157-100704068 : negative

Family Information

Homologous gene family
HOM03P000904
(66 genes in 21 species)
specific family
Orthologous gene family
ORTHO03P021317
(5 genes in 3 species)
specific family

Descriptions

gene_descr
DEXH (Asp-Glu-X-His) box polypeptide 58

Identifiers

Type Value
UniprotQ99J87
MGI1931560

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002376
IEA
Genome Projectimmune system process
GO:0008152
IEA
Genome Projectmetabolic process
GO:0009615
IMP
Genome Projectresponse to virus
GO:0032480
IMP
ISO
IEA
Genome Projectnegative regulation of type I interferon production
GO:0032481
IMP
Genome Projectpositive regulation of type I interferon production
GO:0039534
ISS, ISO
IEA
Genome Projectnegative regulation of MDA-5 signaling pathway
GO:0039536
IMP
ISO
IEA
Genome Projectnegative regulation of RIG-I signaling pathway
GO:0045087
IEA
Genome Projectinnate immune response
GO:0045088
ISO
IEA
Genome Projectregulation of innate immune response
GO:0045824
IMP
ISO
IEA
Genome Projectnegative regulation of innate immune response
GO:0051607
IEA
Genome Projectdefense response to virus
GO:1900245
IMP
Genome Projectpositive regulation of MDA-5 signaling pathway
GO:1900246
IMP
Genome Projectpositive regulation of RIG-I signaling pathway

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
Genome Projectnucleotide binding
GO:0003677
IEA
Genome ProjectDNA binding
GO:0003723
IEA
Genome ProjectRNA binding
GO:0003725
IDA
ISS, ISO
IEA
Genome Projectdouble-stranded RNA binding
GO:0003727
ISS, ISO
IEA
Genome Projectsingle-stranded RNA binding
GO:0004386
IEA
Genome Projecthelicase activity
GO:0005524
IEA
Genome ProjectATP binding
GO:0008270
ISS, ISO
IEA
Genome Projectzinc ion binding
GO:0016787
IEA
Genome Projecthydrolase activity
GO:0016817
IEA
Genome Projecthydrolase activity, acting on acid anhydrides
GO:0046872
IEA
Genome Projectmetal ion binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IDA
IEA
Genome Projectcytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001650Helicase, C-terminal
IPR006935Helicase/UvrB, N-terminal
IPR014001Helicase superfamily 1/2, ATP-binding domain
IPR021673C-terminal domain of RIG-I
IPR027417P-loop containing nucleoside triphosphate hydrolase

No MapMan annotations defined for this gene.