Gene: ENSMUSG00000016529 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000016529
Transcript Identifier
ENSMUST00000016673
Gene Type
Coding gene
Location
1 : 131019912-131024268 : positive

Family Information

Homologous gene family
HOM03P016639
(5 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
interleukin 10

Identifiers

Type Value
UniprotP18893
MGI96537

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001818
IEA
Genome Projectnegative regulation of cytokine production
GO:0002237
ISO
IEA
Genome Projectresponse to molecule of bacterial origin
GO:0002740
ISO
IEA
Genome Projectnegative regulation of cytokine secretion involved in immune response
GO:0002875
IMP
Genome Projectnegative regulation of chronic inflammatory response to antigenic stimulus
GO:0002904
ISO
IEA
Genome Projectpositive regulation of B cell apoptotic process
GO:0006954
ISO, IBA
IEA
Genome Projectinflammatory response
GO:0006955
IBA
IEA
Genome Projectimmune response
GO:0007568
IEA
Genome Projectaging
GO:0010033
IEA
Genome Projectresponse to organic substance
GO:0010468
ISO
IEA
Genome Projectregulation of gene expression
GO:0014823
IEA
Genome Projectresponse to activity
GO:0014854
IEA
Genome Projectresponse to inactivity
GO:0030886
IMP
Genome Projectnegative regulation of myeloid dendritic cell activation
GO:0030889
ISO
IEA
Genome Projectnegative regulation of B cell proliferation
GO:0032496
IEA
Genome Projectresponse to lipopolysaccharide
GO:0032689
IMP
Genome Projectnegative regulation of interferon-gamma production
GO:0032695
IMP
Genome Projectnegative regulation of interleukin-12 production
GO:0032715
ISO
IEA
Genome Projectnegative regulation of interleukin-6 production
GO:0032720
IMP
Genome Projectnegative regulation of tumor necrosis factor production
GO:0032800
ISO
IEA
Genome Projectreceptor biosynthetic process
GO:0032868
IEA
Genome Projectresponse to insulin
GO:0034465
IEA
Genome Projectresponse to carbon monoxide
GO:0042493
IEA
Genome Projectresponse to drug
GO:0042536
IEA
Genome Projectnegative regulation of tumor necrosis factor biosynthetic process
GO:0042742
IDA
Genome Projectdefense response to bacterium
GO:0042832
IDA
Genome Projectdefense response to protozoan
GO:0043066
IEA
Genome Projectnegative regulation of apoptotic process
GO:0044130
IMP
Genome Projectnegative regulation of growth of symbiont in host
GO:0045019
IEA
Genome Projectnegative regulation of nitric oxide biosynthetic process
GO:0045348
IDA
Genome Projectpositive regulation of MHC class II biosynthetic process
GO:0045893
ISO
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0046427
IBA
Genome Projectpositive regulation of JAK-STAT cascade
GO:0050715
ISO
IEA
Genome Projectpositive regulation of cytokine secretion
GO:0050728
IMP
IEA
Genome Projectnegative regulation of inflammatory response
GO:0051045
ISO
IEA
Genome Projectnegative regulation of membrane protein ectodomain proteolysis
GO:0051091
ISO
IEA
Genome Projectpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0051384
ISO
IEA
Genome Projectresponse to glucocorticoid
GO:0051930
IEA
Genome Projectregulation of sensory perception of pain
GO:0060302
ISO
IEA
Genome Projectnegative regulation of cytokine activity
GO:0060670
IMP
Genome Projectbranching involved in labyrinthine layer morphogenesis
GO:0071222
IDA
Genome Projectcellular response to lipopolysaccharide
GO:0071392
IEA
Genome Projectcellular response to estradiol stimulus

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005125
IDA, IMP
IEA
Genome Projectcytokine activity
GO:0005141
IBA
IEA
Genome Projectinterleukin-10 receptor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005576
IEA
Genome Projectextracellular region
GO:0005615
IDA
ISO
IEA
Genome Projectextracellular space

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000098Interleukin-10
IPR009079Four-helical cytokine-like, core
IPR012351Four-helical cytokine, core
IPR020423Interleukin-10, conserved site
IPR020443Interleukin-10/19/20/22/24/26 family

No MapMan annotations defined for this gene.