Gene: ENSMUSG00000016493 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000016493
Transcript Identifier
ENSMUST00000162650
Gene Type
Coding gene
Location
1 : 195041992-195092225 : negative

Family Information

Homologous gene family
HOM03P002827
(33 genes in 5 species)
specific family
Orthologous gene family
ORTHO03P069994
(2 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
CD46 antigen, complement regulatory protein

Identifiers

Type Value
UniprotO88174
MGI1203290

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0002456
ISO
IEA
Genome ProjectT cell mediated immunity
GO:0006508
IEA
Genome Projectproteolysis
GO:0007338
IEA
Genome Projectsingle fertilization
GO:0008593
ISO
IEA
Genome Projectregulation of Notch signaling pathway
GO:0010628
ISO
IEA
Genome Projectpositive regulation of gene expression
GO:0010629
ISO
IEA
Genome Projectnegative regulation of gene expression
GO:0032613
ISO
IEA
Genome Projectinterleukin-10 production
GO:0032733
ISO
IEA
Genome Projectpositive regulation of interleukin-10 production
GO:0035581
ISO
IEA
Genome Projectsequestering of extracellular ligand from receptor
GO:0042102
ISO
IEA
Genome Projectpositive regulation of T cell proliferation
GO:0043086
IEA
Genome Projectnegative regulation of catalytic activity
GO:0043382
ISO
IEA
Genome Projectpositive regulation of memory T cell differentiation
GO:0045591
ISO
IEA
Genome Projectpositive regulation of regulatory T cell differentiation
GO:0045916
IEA
Genome Projectnegative regulation of complement activation
GO:0071636
ISO
IEA
Genome Projectpositive regulation of transforming growth factor beta production

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001848
IEA
Genome Projectcomplement binding
GO:0004175
IEA
Genome Projectendopeptidase activity
GO:0004857
IEA
Genome Projectenzyme inhibitor activity
GO:0045296
ISO
IEA
Genome Projectcadherin binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001669
IEA
Genome Projectacrosomal vesicle
GO:0002079
IEA
Genome Projectinner acrosomal membrane
GO:0005576
IEA
Genome Projectextracellular region
GO:0005737
IEA
Genome Projectcytoplasm
GO:0005794
IEA
Genome ProjectGolgi apparatus
GO:0005925
ISO
IEA
Genome Projectfocal adhesion
GO:0009986
ISO
IEA
Genome Projectcell surface
GO:0016020
IEA
Genome Projectmembrane
GO:0016021
IEA
Genome Projectintegral component of membrane
GO:0016323
IEA
Genome Projectbasolateral plasma membrane
GO:0031410
IEA
Genome Projectcytoplasmic vesicle
GO:0070062
ISO
IEA
Genome Projectextracellular exosome

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR000436Sushi/SCR/CCP domain
IPR017341Membrane cofactor protein CD46

No MapMan annotations defined for this gene.