Gene: ENSMUSG00000016206 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000016206
Transcript Identifier
ENSMUST00000038580
Gene Type
Coding gene
Location
17 : 37270262-37273729 : positive

Family Information

Homologous gene family
HOM03P000618
(85 genes in 2 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
histocompatibility 2, M region locus 3

Identifiers

Type Value
UniprotQ31093
MGI95915

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001916
IDA, IMP
Genome Projectpositive regulation of T cell mediated cytotoxicity
GO:0002237
IDA
Genome Projectresponse to molecule of bacterial origin
GO:0002287
IMP
Genome Projectalpha-beta T cell activation involved in immune response
GO:0002474
IBA
IEA
Genome Projectantigen processing and presentation of peptide antigen via MHC class I
GO:0002476
IDA
Genome Projectantigen processing and presentation of endogenous peptide antigen via MHC class Ib
GO:0002477
IDA
Genome Projectantigen processing and presentation of exogenous peptide antigen via MHC class Ib
GO:0002481
IDA
Genome Projectantigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
GO:0002645
ISO
Genome Projectpositive regulation of tolerance induction
GO:0002666
ISO
Genome Projectpositive regulation of T cell tolerance induction
GO:0002767
ISO
Genome Projectimmune response-inhibiting cell surface receptor signaling pathway
GO:0006955
IEA
Genome Projectimmune response
GO:0019882
IEA
Genome Projectantigen processing and presentation
GO:0032729
IMP
Genome Projectpositive regulation of interferon-gamma production
GO:0032735
ISO
Genome Projectpositive regulation of interleukin-12 production
GO:0042130
ISO
Genome Projectnegative regulation of T cell proliferation
GO:0042742
IDA, IMP
Genome Projectdefense response to bacterium
GO:0045429
IMP
Genome Projectpositive regulation of nitric oxide biosynthetic process
GO:0045591
ISO
Genome Projectpositive regulation of regulatory T cell differentiation
GO:0045954
IMP
Genome Projectpositive regulation of natural killer cell mediated cytotoxicity
GO:2001199
ISO
Genome Projectnegative regulation of dendritic cell differentiation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005102
ISO, IBA
Genome Projectreceptor binding
GO:0042605
IDA, IMP
IEA
Genome Projectpeptide antigen binding
GO:0042803
ISO
Genome Projectprotein homodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009897
IDA
Genome Projectexternal side of plasma membrane
GO:0016020
ISO
IEA
Genome Projectmembrane
GO:0032398
IDA
Genome ProjectMHC class Ib protein complex
GO:0042612
IEA
Genome ProjectMHC class I protein complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001039MHC class I alpha chain, alpha1 alpha2 domains
IPR003006Immunoglobulin/major histocompatibility complex, conserved site
IPR003597Immunoglobulin C1-set
IPR007110Immunoglobulin-like domain
IPR011161MHC class I-like antigen recognition-like
IPR011162MHC classes I/II-like antigen recognition protein
IPR013783Immunoglobulin-like fold
IPR027648MHC class I alpha chain

No MapMan annotations defined for this gene.