Gene: ENSMUSG00000015846 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000015846
Transcript Identifier
ENSMUST00000166775
Gene Type
Coding gene
Location
2 : 27677433-27759688 : positive

Family Information

Homologous gene family
HOM03P000128
(228 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P007410
(11 genes in 3 species)
specific family

Descriptions

gene_descr
retinoid X receptor alpha

Identifiers

Type Value
UniprotP28700
UniprotA2AJP1
MGI98214

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IGI
ISO
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001701
IGI
Genome Projectin utero embryonic development
GO:0001889
IEA
Genome Projectliver development
GO:0001890
IMP
IEA
Genome Projectplacenta development
GO:0001893
IGI
Genome Projectmaternal placenta development
GO:0006351
IEA
Genome Projecttranscription, DNA-templated
GO:0006355
IDA
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IGI
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0006954
IEA
Genome Projectinflammatory response
GO:0007494
IEA
Genome Projectmidgut development
GO:0007507
IMP
TAS
Genome Projectheart development
GO:0007565
IEA
Genome Projectfemale pregnancy
GO:0007566
IGI
Genome Projectembryo implantation
GO:0007568
IEA
Genome Projectaging
GO:0007584
IEA
Genome Projectresponse to nutrient
GO:0008285
IEA
Genome Projectnegative regulation of cell proliferation
GO:0010269
IEA
Genome Projectresponse to selenium ion
GO:0014070
IEA
Genome Projectresponse to organic cyclic compound
GO:0019048
ISO
IEA
Genome Projectmodulation by virus of host morphology or physiology
GO:0031103
IEA
Genome Projectaxon regeneration
GO:0031641
IEA
Genome Projectregulation of myelination
GO:0032526
ISO
IEA
Genome Projectresponse to retinoic acid
GO:0032869
IEA
Genome Projectcellular response to insulin stimulus
GO:0033189
IEA
Genome Projectresponse to vitamin A
GO:0033280
IEA
Genome Projectresponse to vitamin D
GO:0035357
ISO
IEA
Genome Projectperoxisome proliferator activated receptor signaling pathway
GO:0043010
IGI
Genome Projectcamera-type eye development
GO:0043065
IEA
Genome Projectpositive regulation of apoptotic process
GO:0043401
IEA
Genome Projectsteroid hormone mediated signaling pathway
GO:0045471
IEA
Genome Projectresponse to ethanol
GO:0045893
IGI
TAS
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA, IMP, IGI
ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0045994
IGI
Genome Projectpositive regulation of translational initiation by iron
GO:0048384
IDA, IMP
ISO
IEA
Genome Projectretinoic acid receptor signaling pathway
GO:0051289
ISO
IEA
Genome Projectprotein homotetramerization
GO:0051384
IEA
Genome Projectresponse to glucocorticoid
GO:0055010
IMP
Genome Projectventricular cardiac muscle tissue morphogenesis
GO:0055012
IMP, IGI
Genome Projectventricular cardiac muscle cell differentiation
GO:0060038
IMP, IGI
TAS
Genome Projectcardiac muscle cell proliferation
GO:0060528
IMP
Genome Projectsecretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
GO:0060687
IMP
Genome Projectregulation of branching involved in prostate gland morphogenesis
GO:1901522
IDA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
GO:0003007
TAS
Genome Projectheart morphogenesis
GO:0010629
TAS
Genome Projectnegative regulation of gene expression
GO:0055007
TAS
Genome Projectcardiac muscle cell differentiation
GO:0060485
TAS
Genome Projectmesenchyme development
GO:0060978
TAS
Genome Projectangiogenesis involved in coronary vascular morphogenesis
GO:0061032
TAS
Genome Projectvisceral serous pericardium development

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000977
ISO
IEA
Genome ProjectRNA polymerase II regulatory region sequence-specific DNA binding
GO:0003677
IDA, IPI
ISO
IEA
Genome ProjectDNA binding
GO:0003690
IEA
Genome Projectdouble-stranded DNA binding
GO:0003700
IGI
ISO
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003707
IEA
Genome Projectsteroid hormone receptor activity
GO:0004879
IDA
ISO
IEA
Genome ProjectRNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GO:0004886
IDA
Genome Project9-cis retinoic acid receptor activity
GO:0005515
IPI
Genome Projectprotein binding
GO:0008270
IEA
Genome Projectzinc ion binding
GO:0019899
ISO
IEA
Genome Projectenzyme binding
GO:0019904
IEA
Genome Projectprotein domain specific binding
GO:0031490
IDA
Genome Projectchromatin DNA binding
GO:0032403
IEA
Genome Projectprotein complex binding
GO:0042809
ISO
IEA
Genome Projectvitamin D receptor binding
GO:0042974
IEA
Genome Projectretinoic acid receptor binding
GO:0043565
IGI
ISO
IEA
Genome Projectsequence-specific DNA binding
GO:0044212
IDA
ISO
IEA
Genome Projecttranscription regulatory region DNA binding
GO:0044323
ISO
IEA
Genome Projectretinoic acid-responsive element binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0046982
IPI
ISO
IEA
Genome Projectprotein heterodimerization activity
GO:0070644
ISO
IEA
Genome Projectvitamin D response element binding
GO:0008134
IPI
Genome Projecttranscription factor binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000790
ISO
IEA
Genome Projectnuclear chromatin
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0030424
IEA
Genome Projectaxon
GO:0043235
ISO
IEA
Genome Projectreceptor complex
GO:0090575
IDA
ISO
IEA
Genome ProjectRNA polymerase II transcription factor complex
GO:0005654
TAS
Genome Projectnucleoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR000003Retinoid X receptor/HNF4
IPR000536Nuclear hormone receptor, ligand-binding domain
IPR001628Zinc finger, nuclear hormone receptor-type
IPR001723Nuclear hormone receptor
IPR013088Zinc finger, NHR/GATA-type
IPR021780Nuclear/hormone receptor activator site AF-1

No MapMan annotations defined for this gene.