Gene: ENSMUSG00000015579 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000015579
Transcript Identifier
ENSMUST00000015723
Gene Type
Coding gene
Location
17 : 26839022-26841355 : negative

Family Information

Homologous gene family
HOM03P000104
(258 genes in 4 species)
specific family
Orthologous gene family
ORTHO03P068407
(2 genes in 2 species)
specific family

Descriptions

gene_descr
NK2 homeobox 5

Identifiers

Type Value
UniprotP42582
UniprotQ3UQU2
MGI97350

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000122
IDA, IGI
ISO
IEA
Genome Projectnegative regulation of transcription from RNA polymerase II promoter
GO:0001570
IMP
Genome Projectvasculogenesis
GO:0001947
IMP
Genome Projectheart looping
GO:0003007
IMP
Genome Projectheart morphogenesis
GO:0003148
ISO
IEA
Genome Projectoutflow tract septum morphogenesis
GO:0003151
IMP, IGI
Genome Projectoutflow tract morphogenesis
GO:0003161
IGI
ISO
IEA
Genome Projectcardiac conduction system development
GO:0003162
IMP
Genome Projectatrioventricular node development
GO:0003166
IGI
Genome Projectbundle of His development
GO:0003168
IMP
Genome ProjectPurkinje myocyte differentiation
GO:0003208
IMP
Genome Projectcardiac ventricle morphogenesis
GO:0003211
IGI
Genome Projectcardiac ventricle formation
GO:0003221
ISO
IEA
Genome Projectright ventricular cardiac muscle tissue morphogenesis
GO:0003222
IMP
Genome Projectventricular trabecula myocardium morphogenesis
GO:0003278
IMP
Genome Projectapoptotic process involved in heart morphogenesis
GO:0003285
ISO
IEA
Genome Projectseptum secundum development
GO:0003342
IMP
Genome Projectproepicardium development
GO:0003350
IMP
Genome Projectpulmonary myocardium development
GO:0006355
IEA
Genome Projectregulation of transcription, DNA-templated
GO:0006357
IDA
Genome Projectregulation of transcription from RNA polymerase II promoter
GO:0006366
IDA, IMP
ISO
IEA
Genome Projecttranscription from RNA polymerase II promoter
GO:0007275
IEA
Genome Projectmulticellular organismal development
GO:0007492
TAS
Genome Projectendoderm development
GO:0007507
IMP, IGI
Genome Projectheart development
GO:0007512
IMP
ISO
IEA
Genome Projectadult heart development
GO:0008284
IGI
Genome Projectpositive regulation of cell proliferation
GO:0010628
IDA
Genome Projectpositive regulation of gene expression
GO:0010667
IMP
ISO
IEA
Genome Projectnegative regulation of cardiac muscle cell apoptotic process
GO:0010735
IDA
Genome Projectpositive regulation of transcription via serum response element binding
GO:0010765
IMP
Genome Projectpositive regulation of sodium ion transport
GO:0010832
ISO
IEA
Genome Projectnegative regulation of myotube differentiation
GO:0030097
IMP
Genome Projecthemopoiesis
GO:0030154
IGI
Genome Projectcell differentiation
GO:0030509
IDA
Genome ProjectBMP signaling pathway
GO:0030878
IMP
ISO
IEA
Genome Projectthyroid gland development
GO:0035050
IGI
Genome Projectembryonic heart tube development
GO:0043066
IGI
Genome Projectnegative regulation of apoptotic process
GO:0043586
TAS
Genome Projecttongue development
GO:0045214
IGI
Genome Projectsarcomere organization
GO:0045666
ISO
IEA
Genome Projectpositive regulation of neuron differentiation
GO:0045823
IMP
Genome Projectpositive regulation of heart contraction
GO:0045893
IDA
ISO
IEA
Genome Projectpositive regulation of transcription, DNA-templated
GO:0045944
IDA, IMP, IGI
ISO
IEA
Genome Projectpositive regulation of transcription from RNA polymerase II promoter
GO:0048536
IGI
ISO
TAS, IEA
Genome Projectspleen development
GO:0048738
IMP
Genome Projectcardiac muscle tissue development
GO:0051891
IMP
Genome Projectpositive regulation of cardioblast differentiation
GO:0055005
IMP
Genome Projectventricular cardiac myofibril assembly
GO:0055007
IDA, IMP, IGI
TAS
Genome Projectcardiac muscle cell differentiation
GO:0055008
ISO
IEA
Genome Projectcardiac muscle tissue morphogenesis
GO:0055014
TAS
Genome Projectatrial cardiac muscle cell development
GO:0055015
TAS
Genome Projectventricular cardiac muscle cell development
GO:0055117
IMP
Genome Projectregulation of cardiac muscle contraction
GO:0060037
IGI
Genome Projectpharyngeal system development
GO:0060038
IGI
Genome Projectcardiac muscle cell proliferation
GO:0060043
IDA
Genome Projectregulation of cardiac muscle cell proliferation
GO:0060047
IGI
Genome Projectheart contraction
GO:0060048
IMP
Genome Projectcardiac muscle contraction
GO:0060070
IDA
Genome Projectcanonical Wnt signaling pathway
GO:0060261
IDA
Genome Projectpositive regulation of transcription initiation from RNA polymerase II promoter
GO:0060347
IMP
Genome Projectheart trabecula formation
GO:0060412
ISO
IEA
Genome Projectventricular septum morphogenesis
GO:0060413
ISO
IEA
Genome Projectatrial septum morphogenesis
GO:0060928
IMP
Genome Projectatrioventricular node cell development
GO:0060929
IMP
Genome Projectatrioventricular node cell fate commitment
GO:0060971
IMP
Genome Projectembryonic heart tube left/right pattern formation
GO:0072358
IGI
Genome Projectcardiovascular system development
GO:0090090
IDA
Genome Projectnegative regulation of canonical Wnt signaling pathway
GO:1903779
IMP
Genome Projectregulation of cardiac conduction

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000978
ISO
IEA
Genome ProjectRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077
ISO
IEA
Genome Projecttranscriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
GO:0001104
IMP
Genome ProjectRNA polymerase II transcription cofactor activity
GO:0001190
IMP
Genome Projecttranscriptional activator activity, RNA polymerase II transcription factor binding
GO:0001228
IDA
ISO
Genome Projecttranscriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
GO:0003677
IDA
ISO
IEA
Genome ProjectDNA binding
GO:0003682
IDA
ISO
IEA
Genome Projectchromatin binding
GO:0003700
IDA
ISO
IEA
Genome Projecttranscription factor activity, sequence-specific DNA binding
GO:0003705
IDA
Genome Projecttranscription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0008134
ISO
IEA
Genome Projecttranscription factor binding
GO:0010736
IDA
Genome Projectserum response element binding
GO:0042803
IDA
Genome Projectprotein homodimerization activity
GO:0043565
ISO
IEA
Genome Projectsequence-specific DNA binding
GO:0044212
ISO
IEA
Genome Projecttranscription regulatory region DNA binding
GO:0046982
IPI
Genome Projectprotein heterodimerization activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISO
IEA
Genome Projectnucleus
GO:0005667
IDA
Genome Projecttranscription factor complex
GO:0005737
IDA
Genome Projectcytoplasm
GO:0090575
ISO
IEA
Genome ProjectRNA polymerase II transcription factor complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001356Homeobox domain
IPR009057Homeodomain-like
IPR017970Homeobox, conserved site
IPR020479Homeodomain, metazoa

No MapMan annotations defined for this gene.