Gene: ENSMUSG00000015143 (Mus musculus)

Overview top

Gene Identifier
ENSMUSG00000015143
Transcript Identifier
ENSMUST00000021554
Gene Type
Coding gene
Location
12 : 80168322-80260091 : negative

Family Information

Homologous gene family
HOM03P000481
(99 genes in 11 species)
specific family
Orthologous gene family
ORTHO03P006041
(14 genes in 10 species)
specific family
Duplication type
Tandem duplicate

Descriptions

gene_descr
actinin, alpha 1

Identifiers

Type Value
UniprotQ7TPR4
MGI2137706

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Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0007015
ISO
Genome Projectactin filament organization
GO:0030220
ISO
Genome Projectplatelet formation
GO:0030865
TAS
Genome Projectcortical cytoskeleton organization
GO:0036344
ISO
Genome Projectplatelet morphogenesis
GO:0048041
ISO
IEA
Genome Projectfocal adhesion assembly
GO:0051017
IDA
IEA
Genome Projectactin filament bundle assembly
GO:0051271
ISO
IEA
Genome Projectnegative regulation of cellular component movement
GO:0051639
ISO
Genome Projectactin filament network formation
GO:0051764
IEA
Genome Projectactin crosslink formation
GO:1903506
ISO
IEA
Genome Projectregulation of nucleic acid-templated transcription

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003725
ISO
IEA
Genome Projectdouble-stranded RNA binding
GO:0003779
IEA
Genome Projectactin binding
GO:0005178
IPI
ISO
IEA
Genome Projectintegrin binding
GO:0005509
IEA
Genome Projectcalcium ion binding
GO:0005515
IPI
Genome Projectprotein binding
GO:0017166
IDA
ISO
IEA
Genome Projectvinculin binding
GO:0030374
ISO
IEA
Genome Projectligand-dependent nuclear receptor transcription coactivator activity
GO:0042803
IDA
ISO
TAS
Genome Projectprotein homodimerization activity
GO:0044325
ISO
IEA
Genome Projection channel binding
GO:0046872
IEA
Genome Projectmetal ion binding
GO:0051015
IDA
ISO
IEA
Genome Projectactin filament binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0001725
IDA
ISO
TAS
Genome Projectstress fiber
GO:0001726
ISO
IEA
Genome Projectruffle
GO:0005615
ISO
IEA
Genome Projectextracellular space
GO:0005622
IDA
ISO
Genome Projectintracellular
GO:0005737
ISO
IEA
Genome Projectcytoplasm
GO:0005856
IEA
Genome Projectcytoskeleton
GO:0005886
IEA
Genome Projectplasma membrane
GO:0005903
IDA
Genome Projectbrush border
GO:0005911
ISO
Genome Projectcell-cell junction
GO:0005916
IDA
Genome Projectfascia adherens
GO:0005925
ISO
TAS, IEA
Genome Projectfocal adhesion
GO:0016020
IEA
Genome Projectmembrane
GO:0030018
IDA
IEA
Genome ProjectZ disc
GO:0030054
IEA
Genome Projectcell junction
GO:0030141
NAS
Genome Projectsecretory granule
GO:0030863
TAS
Genome Projectcortical cytoskeleton
GO:0032127
TAS
Genome Projectdense core granule membrane
GO:0042995
ISO
IEA
Genome Projectcell projection
GO:0070062
ISO
IEA
Genome Projectextracellular exosome
GO:0005884
ISO
Genome Projectactin filament

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources:   Primary     Orthology     Homology  
Show redundant parents:  
 
InterPro Description
IPR001589Actinin-type actin-binding domain, conserved site
IPR001715Calponin homology domain
IPR002017Spectrin repeat
IPR002048EF-hand domain
IPR011992EF-hand domain pair
IPR014837EF-hand, Ca insensitive
IPR018159Spectrin/alpha-actinin
IPR018247EF-Hand 1, calcium-binding site
IPR026921Alpha-actinin 1

No MapMan annotations defined for this gene.